A naloxone admixture to prevent opioid-induced pruritus in children: a randomized controlled trial

Conclusion This admixture of naloxone and morphine in normal saline did not decrease the incidence or severity of OIP in this sample. Separate administration of naloxone may be the more effective strategy for prevention of OIP. This trial was registered at ClinicalTrials.gov (NCT01071057).

http://link.springer.com/10.1007/s12630-015-0380-5

Source: Canadian Journal of Anesthesia - July 18, 2015 Category: Anesthesiology Source Type: research