In Vitro Assessment of the Assisted Bidirectional Glenn Procedure for Stage One Single Ventricle Repair

We report time-based comparisons with numerical simulations for the three surgical variants tested. The ABG circulation demonstrated an increase of 30–38% in pulmonary flow with a 2–3.7 mmHg increase in SVC pressure compared to the Glenn and a 4–14% higher systemic OD than either the Norwood or the Glenn. The nozzle/shunt diameter ratio affected the local hemodynamics. These experimental results agreed with those of the numerical model: mean flow values were not significantly different (p > 0.05) while mean pressures were comparable within 1.2 mmHg. The results verify the approaches providing two tools to study this complicated circulation. Using a realistic experimental model we demonstrate the performance of a novel surgical procedure with potential to improve patient hemodynamics in early palliation of the univentricular circulation.
Source: Cardiovascular Engineering and Technology - Category: Cardiology Source Type: research