Relationship between physical activity and markers of oxidative stress in independent community-living elderly individuals.

Relationship between physical activity and markers of oxidative stress in independent community-living elderly individuals.
Exp Gerontol. 2015 Jul 11;
Authors: Fraile-Bermúdez AB, Kortajarena M, Zarrazquin I, Maquibar A, Yanguas JJ, Sánchez-Fernández CE, Gil J, Irazusta A, Ruiz-Litago F
Abstract
The aim of the present study was to examine the relationship between objective data of physical activity and markers of oxidative stress in older men and women. Participants were old adults, aged≥60years (61 women and 34 men) who were all capable of performing basic daily activities by themselves and lived on their own. To describe physical activity we used objective data measured by accelerometers which record active and sedentary periods during everyday life for five days. Determination of oxidative stress was conducted from three perspectives: determination plasma total antioxidant status (TAS), plasma antioxidant enzyme activities, i.e., glutathione peroxidase (GPx), catalase (CAT) and superoxide dismutase (SOD), and membrane lipid peroxidation (TBARS). In the group of women, those who met physical activity recommendations (WR) had lower level of TAS. In addition, the moderate to vigorous physical activity (MVPA) was negatively correlated with TAS. Simultaneously, MVPA was correlated with increase in the GPx antioxidant enzyme activity, and the counts per minute (cpm) were positively correlated with CAT activity. In the group of men,...

Source: Experimental Gerontology - July 11, 2015 Category: Geriatrics Authors: Fraile-Bermúdez AB, Kortajarena M, Zarrazquin I, Maquibar A, Yanguas JJ, Sánchez-Fernández CE, Gil J, Irazusta A, Ruiz-Litago F Tags: Exp Gerontol Source Type: research