Possible role of TGF β- 1 in inflammatory pseudotumor associated with multiple neuroendocrine tumors of the small intestine

Discussion Based on the current literature and our previous experiences, we can state that IPT are an aberrant secondary immunological process possibly induced by excessive TGF- β 1 and not a neoplasia. Nevertheless, the tumorous behavior points to a continuity between inflammation and neoplasia. Differential diagnoses and the potential molecular pathogenesis are further discussed.
Source: Pathology Research and Practice - Category: Pathology Source Type: research