Statin use and non-alcoholic steatohepatitis in at risk individuals

Following the trail of the obesity epidemics, Non-alcoholic fatty liver disease (NAFLD), defined by hepatic triglycerides content exceeding 5% in the absence of at risk alcohol intake [1], has become the leading cause of liver disease [2,3]. This condition is epidemiologically associated with metabolic syndrome and insulin resistance, that increases the hepatic flux of free fatty acids from adipose tissue, and leads to de novo lipogenesis [4–6].

Source: Journal of Hepatology - May 13, 2015 Category: Gastroenterology Authors: Paola Dongiovanni, Salvatore Petta, Ville Mannisto, Rosellina Margherita Mancina, Rosaria Pipitone, Vesa Karja, Marco Maggioni, Pirjo Kakela, Olov Wiklund, Enrico Mozzi, Stefania Grimaudo, Dorota Kaminska, Raffaela Rametta, Antonio Craxi, Silvia Fargion, Tags: Research Article Source Type: research