4 Frustrating Facts About PCOS... and What They Mean for You
Depression. Weight gain. Increased acne and hair growth. Irregular periods. Infertility. These are some of the most notable symptoms of one of the most common hormonal, metabolic and reproductive disorders found in women: polycystic ovary syndrome (PCOS). So, what is PCOS exactly? Women with PCOS have too many male hormones and not enough female hormones, which interferes with ovulation. With PCOS, the ovaries are typically enlarged and may even contain multiple small cyst-like structures (immature ovarian follicles). If left untreated, this hormone imbalance can affect everything from a woman's menstrual cycle, to her appearance, to her ability to have children, to her overall health. Unfortunately, this disorder is one of the most misunderstood, under-diagnosed and under-funded conditions affecting women's health. It's time to step up and educate ourselves. So here are four frustrating facts about PCOS and what they mean for you: 1. Between five to 10 percent of women of childbearing age in the United States, or roughly 5 million, have PCOS. That percentage makes it one of the most common hormonal endocrine disorders in women. What's more, it also makes it the most common cause of female infertility. According to Sasha Ottey, founder and executive director of PCOS Challenge, Inc., "PCOS is one of the most critical, underserved, under-diagnosed and under-funded conditions affecting women's health. We need the help of media, government agencies and funding sources to...
In this study, we observed that Iba-1 and P2X4R expression is increased in microglia treated with MCP-1, and blockade with a selective CCR2 antagonist RS-504393 suppressed microglia activation and reduced P2X4R expression in cultured microglia. In response to MCP-1, the expression level of p-Akt was also increased and RS-504393 inhibited the increase. Besides, PI3K inhibitor LY 294002 could attenuate MCP-1-induced P2X4R expression in cultured microglia. MCP-1 was found to be associated with P2X4R expression and mechanical allodynia induced by CIBP in vivo since the expression of MCP-1 was increased in CIBP and RS-504393 al...
In conclusion, overweight patients with hypertrophic muscles pose a risk for brachial plexus entrapment injury by pectoral muscles during prone-position surgery, and therefore it would be more effective to use a wide chest pad to reduce the pressure on the pectoral muscles to prevent it from being pushed out toward the axillary fossa.
The patches are designed to treat diabetic leg and foot ulcers – long-term wounds that often fail to close for months or even years and affect 115,000 Britons.
CONCLUSION: High-quality, prospective, randomized trials that would enable a definitive judgment of the efficacy of HBOT are currently lacking. PMID: 30765023 [PubMed - in process]
I never miss a check-up, even ‘embarrassing’ ones, and I’m first in line for a flu shot. Every ache and pain has me calling my GP, convinced that it’s cancer, says JO ELVIN.
Publication date: Available online 16 February 2019Source: LWTAuthor(s): Silke Großhagauer, Raphael Steinschaden, Marc PignitterAbstractConsumption of cold pressed oils rich in polyunsaturated fatty acids (PUFA) is considered healthy. However, these oils are characterized by a lack of oxidative stability, leading to the accumulation of lipid oxidation products, which have been shown to have detrimental effects on health. Thus, it is of utmost interest to find strategies to increase the oxidative stability of PUFA-rich oils. The progress of lipid oxidation in edible oils has been shown to be influenced by many factors...
A combination of Merck&Co's immunotherapy Keytruda and Pfizer Inc's Inlyta helped patients with advanced kidney cancer live longer than those receiving and older Pfizer standalone therapy, according to data from a late-stage study presented on Saturday.
The way doctors typically approach kidney cancer treatment could be evolving.
CONCLUSIONS: Lighten UP! Program confirmed its positive effects for enhancing EWB in older adults living in multiple community settings. CLINICAL IMPLICATIONS: Programs that sustain or enhance EWB in older adults can be expected to yield improvements in diverse aspects of mental and physical health. PMID: 30767628 [PubMed - as supplied by publisher]
Authors: Kikuchi S, Kubota T, Kuroda S, Nishizaki M, Kagawa S, Kato H, Okada H, Fujiwara T Abstract Endoscopic ultrasound (EUS)-guided transgastric drainage has been performed as a less invasive procedure for pancreatic fistulas and intra-abdominal abscesses occurring after surgery in recent years. However, there are no reports of EUS-guided transgastric drainage of intra-abdominal abscesses following gastrectomy. This case report describes 2 patients who developed an intra-abdominal abscess following gastrectomy and underwent EUS-guided transgastric drainage. Both patients underwent laparoscopy-assisted distal gas...
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