4 Frustrating Facts About PCOS... and What They Mean for You

Depression. Weight gain. Increased acne and hair growth. Irregular periods. Infertility. These are some of the most notable symptoms of one of the most common hormonal, metabolic and reproductive disorders found in women: polycystic ovary syndrome (PCOS). So, what is PCOS exactly? Women with PCOS have too many male hormones and not enough female hormones, which interferes with ovulation. With PCOS, the ovaries are typically enlarged and may even contain multiple small cyst-like structures (immature ovarian follicles). If left untreated, this hormone imbalance can affect everything from a woman's menstrual cycle, to her appearance, to her ability to have children, to her overall health. Unfortunately, this disorder is one of the most misunderstood, under-diagnosed and under-funded conditions affecting women's health. It's time to step up and educate ourselves. So here are four frustrating facts about PCOS and what they mean for you: 1. Between five to 10 percent of women of childbearing age in the United States, or roughly 5 million, have PCOS. That percentage makes it one of the most common hormonal endocrine disorders in women. What's more, it also makes it the most common cause of female infertility. According to Sasha Ottey, founder and executive director of PCOS Challenge, Inc., "PCOS is one of the most critical, underserved, under-diagnosed and under-funded conditions affecting women's health. We need the help of media, government agencies and funding sources to...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news

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Publication date: Available online 18 October 2018Source: Journal of Molecular LiquidsAuthor(s): H. Abramczyk, A. Imiela, A. ƚliwiƄskaAbstractLipids play an important role in many cellular processes. Raman-driven microscopy is one of the most powerful technique for analyzing the properties of lipids in cellular compartments offering lipid compositional mapping and more precise, faster, simpler, and nondestructive measurements. Recent advances in Raman imaging (RI) have greatly progressed lipidomic analysis, such as lipid droplet content, lipid phenotype, fatty acid composition, spatial distribution and drug treatment res...
Source: Journal of Molecular Liquids - Category: Molecular Biology Source Type: research
Publication date: Available online 18 October 2018Source: Journal of Molecular LiquidsAuthor(s): Xianghong Li, Shuduan Deng, Tong Lin, Xiaoguang Xie, Xin XuAbstractThe inhibition effect of triazolyl blue tetrazolium bromide (TBTB) on cold rolled steel (CRS) in three chlorinated acetic acids of monochloroacetic acid (ClCH2COOH), dichloroacetic acid (Cl2CHCOOH) and trichloroacetic acid (Cl3CCOOH) was studied by weight loss, potentiodynamic polarization curves, electrochemical impedance spectroscopy (EIS) and scanning electron microscopy (SEM) methods. Meanwhile, the adsorption mechanism of TBT+ (organic part of TBTB) was the...
Source: Journal of Molecular Liquids - Category: Molecular Biology Source Type: research
Publication date: Available online 18 October 2018Source: Journal of Molecular LiquidsAuthor(s): Mostafa Zamani, Ehsan Naderi, Mozhgan Aghajanzadeh, Mahmoud Naseri, Ali Sharafi, Hossein DanafarAbstractThe present paper aimed to synthesize, using thermal-treatment method, a variety of Co1-XZnxFe2O4-based nanocarriers (NCs) as Dual-controlled and targeted drug delivery systems (DDS) and provide a new structure as NCs suitable for the loading and pH-responsive characteristics of the chemotherapeutic curcumin (CUR). To study the structure, surface morphology, surface charge and magnetic properties of NCs, X-ray diffraction (XR...
Source: Journal of Molecular Liquids - Category: Molecular Biology Source Type: research
This study examined the role of H2S in drug resistance in liver cancer cells.Materials and methodsHuman primary hepatocellular carcinoma cell line (HepG2) and doxorubicin (Dox)-resistant cells were used in this study. Cell survival was analyzed by MTT, Annexin V-FITC/propidium iodide staining and clonogenic assay. Western blotting was used for analysis of protein expression, and immunoprecipitation was used to determine interactions of LXR/RXR.Key findingsThe expression of H2S-generating enzyme cystathionine gamma-lyase (CSE) was inhibited by doxorubicin treatment in HepG2 cells, and H2S sensitized Dox-inhibited cell survi...
Source: Life Sciences - Category: Biology Source Type: research
Publication date: Available online 18 October 2018Source: Life SciencesAuthor(s): Pratibha Chauhan, Akhilesh Kumar Tamrakar, Sunil Mahajan, G.B.K.S. PrasadAbstractAimThe present study was undertaken to develop a Curcumin nanoparticle system with chitosan as a hydrophilic carrier. In addition, the anti-diabetic potential of curcumin loaded chitosan nanoparticles were assessed in comparison to those of free curcumin by examining the anti-hyperglycemic efficacy using in vitro assays.MethodsCurcumin loaded chitosan nanoparticles were prepared and characterized for particle size by transmission electron microscopy, FT-IR, diffe...
Source: Life Sciences - Category: Biology Source Type: research
A Houston hospital is replacing the surgical director of its renowned heart transplant programs with two veteran transplant surgeons and a veteran transplant program executive
Source: ABC News: Health - Category: Consumer Health News Tags: Health Source Type: news
This study was based on the fact that, overall mass, charge and size of a protein changes after interaction with charged ligands such as metal ions, which affects the electrophoretic movement of the analyte protein under the influence of electroosmotic flow. This alteration in electrophoretic mobility of the analyte is proportional to the strength of interaction between the two species and is utilized to calculate the binding results. The mobility ratio (R) of an EOF marker (injected in same run) and the analyte enzyme was determined and the binding result was expressed as the normalized difference of the mobility ratios o...
Source: Microchemical Journal - Category: Chemistry Source Type: research
Publication date: Available online 18 October 2018Source: Genes &DiseasesAuthor(s): Xingxing Zang
Source: Genes and Diseases - Category: Genetics & Stem Cells Source Type: research
Publication date: Available online 18 October 2018Source: Comparative Biochemistry and Physiology Part D: Genomics and ProteomicsAuthor(s): Aimee Lee S. Houde, Angela D. Schulze, Karia H. Kaukinen, Jeffrey Strohm, David A. Patterson, Terry D. Beacham, Anthony P. Farrell, Scott G. Hinch, Kristina M. MillerAbstractThere is a paucity of information on the physiological changes that occur over the course of salmon early marine migration. Here we aim to provide insight on juvenile Coho salmon (Oncorhynchus kisutch) physiology using the changes in gene expression (cGRASP 44K microarray) of four tissues (brain, gill, muscle, and ...
Source: Comparative Biochemistry and Physiology Part D: Genomics and Proteomics - Category: Genetics & Stem Cells Source Type: research
A Houston hospital is replacing the surgical director of its renowned heart transplant programs with two veteran transplant surgeons and a veteran transplant program executive
Source: ABC News: Health - Category: Consumer Health News Tags: Health Source Type: news
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