Mozart's music in children with drug-refractory epileptic encephalopathies

Publication date: September 2015 Source:Epilepsy & Behavior, Volume 50 Author(s): Giangennaro Coppola , Annacarmela Toro , Francesca Felicia Operto , Giuseppe Ferrarioli , Simone Pisano , Andrea Viggiano , Alberto Verrotti Mozart's sonata for two pianos in D major, K448, has been shown to decrease interictal EEG discharges and recurrence of clinical seizures in both adults and young patients. In this prospective, open-label study, we evaluated the effect of listening to a set of Mozart's compositions, according to the Tomatis method, on sleep quality and behavioral disorders, including auto-/hetero-aggression, irritability, and hyperactivity, in a group of children and adolescents with drug-resistant epilepsy. The study group was composed of 11 outpatients (7 males and 4 females), between 1.5years and 21years of age (mean age: 11.9years), all suffering from drug-resistant epileptic encephalopathy (n=11). All of them had a severe/profound intellectual disability associated with cerebral palsy. During the study period, each patient had to listen to a set of Mozart's compositions 2h per day for fifteen days for a total of 30h, which could be distributed over the day depending on the habits and compliance of each patient. The music was filtered by a device preferably delivering higher sound frequencies (>3000Hz) according to the Tomatis principles. The antiepileptic drug therapy remained unchanged throughout the study period. During the 15-day music therapy, 2 out of 11 ...
Source: Epilepsy and Behavior - Category: Neurology Source Type: research

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Conclusions: ABL is common (57.1%). It occurs at an early stage (within 3 months) and typically follows a non-progressive natural history with stable radiographic features after the first year. Most ABL cases are mild, but severe ABL occurs in approximately 3% of CDAs. ABL does not affect the patients' clinical outcome or the requirement for revision surgery. Surgeons should thus treat patients undergoing CDA considering ABL. PMID: 30326692 [PubMed - as supplied by publisher]
Source: Asian Spine Journal - Category: Orthopaedics Tags: Asian Spine J Source Type: research
Authors: Ansari NN, Komesh S, Naghdi S, Fakhari Z, Alaei P Abstract Study Design: A prospective, within-group cohort study of 46 patients with chronic low-back pain (CLBP). Purpose: To assess the responsiveness of the Persian Functional Rating Index (PFRI) and to determine the minimal clinically important change (MCIC) of the PFRI in a cohort of patients with CLBP. Overview of Literature: The FRI is an instrument for assessing pain and disability in patients with low-back pain. No study so far has examined the responsiveness of the PFRI. Methods: Forty-six patients with CLBP with a mean age of 50.33&plu...
Source: Asian Spine Journal - Category: Orthopaedics Tags: Asian Spine J Source Type: research
Authors: Mohamad G, Amritanand R, David KS, Krishnan V, Arockiaraj J Abstract Study Design: Retrospective case series. Purpose: The aim of this study was to analyze functional and radiological outcomes in patients with culture-negative pyogenic vertebral osteomyelitis (PVO). Overview of Literature: There were only few literature available for these group of patients. Methods: Patients with biopsy-positive but culture-negative PVO were included. We analyzed records for data on demography, comorbidities, coexisting infections, neurological status, prior antibiotic therapy, pre- and postoperative erythrocy...
Source: Asian Spine Journal - Category: Orthopaedics Tags: Asian Spine J Source Type: research
Authors: Gadia A, Shah K, Nene A Abstract Cervical kyphosis is a rare condition that can cause significant functional disability and myelopathy. Deciding the appropriate treatment for such deformities is challenging for the surgeon. Patients often present with axial neck pain, and it is not uncommon to find coexisting radiculopathy or myelopathy. The optimal approach for addressing this complex issue remains controversial. A comprehensive surgical plan based on knowledge of the pathology and biomechanics is important for kyphosis correction. Here we reviewed diagnoses of the cervical spine along with the literature...
Source: Asian Spine Journal - Category: Orthopaedics Tags: Asian Spine J Source Type: research
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Source: Asian Spine Journal - Category: Orthopaedics Tags: Asian Spine J Source Type: research
Publication date: Available online 17 October 2018Source: Neuroscience LettersAuthor(s): Benjamin Sack, Katja Broer, Silke AndersAbstractObservational and experimental studies have shown that sleep deprivation disinhibits emotional responses to disturbing and rewarding external events. On the other hand, most studies on sleep deprivation and interpersonal emotion recognition report that sensitivity to others’ emotions is dampened after sleep deprivation. This is at odds with current neuroscientific theories of social cognition that assume that affective experiences and emotion recognition in others are closely tied a...
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
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Source: NeuroImage - Category: Neuroscience Source Type: research
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Source: Neurological Research - Category: Neurology Tags: Neurol Res Source Type: research
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Source: Journal of Motor Behavior - Category: Neurology Tags: J Mot Behav Source Type: research
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Source: Ciencia e Saude Coletiva - Category: Occupational Health Source Type: research
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