Increased cardiovascular and metabolic morbidity in patients with 21-hydroxylase deficiency: a Swedish population-based national cohort study.

CONCLUSIONS: CAH was associated with excess cardiovascular and metabolic morbidity but the mechanism is not certain as the glucocorticoids were not assessed. Hypothyroidism and obesitymay be an effect of close observation. However, more severe conditions were presumably detected equally in patients and controls. Screening for diabetes and other metabolic disorders which increase cardiovascular risk is important. PMID: 26126207 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/26126207?dopt=Abstract

Source: The Journal of Clinical Endocrinology and Metabolism - June 30, 2015 Category: Endocrinology Authors: Falhammar H, Frisén L, Linden Hirschberg A, Norrby C, Almqvist C, Nordenskjöld A, Nordenström A Tags: J Clin Endocrinol Metab Source Type: research