Log in to search using one of your social media accounts:

 

UCLA patient is first to receive successful heart transplant after using experimental 50cc Total Artificial Heart

A petite 44-year-old woman has received a successful heart transplant at Ronald Reagan UCLA Medical Center, thanks to an experimental Total Artificial Heart designed for smaller patients.  The UCLA patient is the first person in California to receive the smaller Total Artificial Heart, and the first patient in the world with the device to be bridged to a successful heart transplant — that is, to go from needing a transplant to receiving one. The 50cc SynCardia temporary Total Artificial Heart is a smaller investigational version of the larger 70cc SynCardia heart, which was approved for use in people awaiting a transplant by the Federal Food and Drug Administration in 2004 and has been used by more than 1,440 patients worldwide. The 50cc device is designed to be used by smaller patients — including most women, some men and many adolescents — with end-stage biventricular heart failure, where both sides of the heart are failing to pump enough blood to sustain the body. The device provides mechanical support until a donor heart can be found.   Nemah Kahala, a wife and mother of five, was transferred to UCLA from Kaiser Permanente Los Angeles Medical Center in March.  She was suffering from restrictive heart muscle disease and in critical condition.  Her heart failure was so advanced that repair surgery and other mechanical assist devices could not help.    Kahala was placed on a life support system called extra corpo...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news

Related Links:

Authors: Rafiq K Abstract Cardiovascular disease (CVD) is a class of diseases that involve disorders of heart and blood vessels, including: hypertension, coronary heart disease, cerebrovascular disease, peripheral vascular disease, which finally lead to heart failure (HF). There are several treatments available all over the world, but still CVD and heart failure became the number one problem causing death every year worldwide. Both experimental and clinical studies have shown a role for inflammation in the pathogenesis of heart failure. This seems related to an imbalance between pro-inflammatory and anti-inflammato...
Source: Cardiovascular and Hematological Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Cardiovasc Hematol Disord Drug Targets Source Type: research
The objective of the present study was to assess the possible utility of the difference in coronary sinus diameter to quantify stable atherosclerotic plaque(s) using 256-slice coronary computed tomographic angiography. MATERIAL AND METHODS A total of 336 patients were divided into 2 groups with 168 patients each. Patients who had heart failure were included in the study group and those who did not were included in the non-study group. Patients were subjected to cross-sectional study. Cardiovascular images were performed with 256-slice coronary computed tomographic angiography with a prospective electrocardiogram and clinic...
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
We report the case of a patient with Steinert disease showing an early onset ventricular dysfunction due to chronic right ventricular apical pacing, in which an epicardial left ventricular lead implantation was performed following the failure of the percutaneous attempt. As no relief in symptoms of heart failure, nor an improvement of left ventricular ejection fraction and reverse remodelling was observed six months later, the patient was addressed to the heart transplantation. PMID: 29770365 [PubMed - in process]
Source: Acta Myologica - Category: Neurology Tags: Acta Myol Source Type: research
Authors: Khoury EE, Kinaneh S, Aronson D, Amir O, Ghanim D, Volinsky N, Azzam Z, Abassi Z Abstract Congestive heart failure (CHF) often leads to progressive cardiac hypertrophy and salt/water retention as evident by peripheral and lung edema. Although the pathogenesis of CHF remains largely unclarified, it is widely accepted that neurohormonal changes and inflammatory processes are profoundly involved in structural and functional deterioration of vital organs including, heart, kidney and lungs. Corin, a cardiac serine protease, is responsible for converting pro-ANP and pro-BNP to biologically active natriuretic pep...
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
Conclusions: Galectin-3 is directly associated with early myocardial inflammation post-MI and may represent a potential target for therapeutic inhibition. PMID: 29769800 [PubMed]
Source: Biomarker Insights - Category: General Medicine Authors: Tags: Biomark Insights Source Type: research
We appreciate the interest of Wu et  al in our work and welcome their insightful comment.1 In their letter, they describe an interesting case of heart failure resulting from aorta-pulmonary artery fistula in an elderly patient who initially presented with chest discomfort.2 Although the authors do not elaborate on the potential cause , aorta-pulmonary artery fistula can occur secondary to local rupture in the aorta with severe degenerative disease in the setting of an aneurysm, trauma, or infection.
Source: The American Journal of Medicine - Category: General Medicine Authors: Tags: Letter Source Type: research
We read the article “Arteriovenous fistula: an uncommon cause of heart failure,” reported by Koratala et al,1 with great interest. The study reported a 72-year-old patient with arteriovenous fistula that resulted in heart failure. Recently we encountered an 84-year-old patient suffering from aorta–aorta fistula w ith chest discomfort. The initial chest computed tomography angiography of the patient showed a descending aorta–pulmonary aorta fistula with collateral vessels (Figure). However, the chest pain was considered as unstable angina, for which the patient received 2 coronary stents.
Source: The American Journal of Medicine - Category: General Medicine Authors: Tags: Letter Source Type: research
Source: Brazilian Journal of Cardiovascular Surgery - Category: Cardiology Source Type: research
CONCLUSIONS: Ultrasound of the IJV may be a useful tool for the diagnosis of ADHF because it is easy to measure and requires little skill. It is also not affected by patient body habitus. PMID: 29761678 [PubMed - in process]
Source: The Israel Medical Association Journal - Category: General Medicine Tags: Isr Med Assoc J Source Type: research
Authors: Zalts R, Twizer T, Leiba R, Karban A Abstract BACKGROUND: The identification of the etiology of a pleural effusion can be difficult. Measurement of serum B-type natriuretic peptide (BNP) levels is helpful in the diagnosis of congestive heart failure (CHF) as a cause of respiratory failure, but pleural fluid BNP measurement is still not part of the workup for pleural effusion. OBJECTIVES: To identify the correlation between pleural fluid BNP levels and clinical diagnosis. METHODS: In this cross-sectional study, data from 107 patients admitted to the department of internal medicine between November 2...
Source: The Israel Medical Association Journal - Category: General Medicine Tags: Isr Med Assoc J Source Type: research
More News: Cardiology | Emergency Medicine | Food and Drug Administration (FDA) | Gastroschisis Repair | Health | Heart | Heart Failure | Heart Transplant | Hospitals | Intensive Care | Lung Transplant | Physical Therapy | Study | Transplant Surgery | Transplants | Universities & Medical Training | Women