Mixed Results for Brachytherapy in Breast Cancer (CME/CE)
(MedPage Today) -- Older breast cancer patients had an increased rate of subsequent mastectomy if they received brachytherapy instead of external-beam radiation therapy after lumpectomy but fared better than patients who received no radiation, investigators reported.
CONCLUSION: In our experience we always underwent to ALND all patients with micrometastases. In the light of the results we observed our attitude no longer provides for the axillary lymphadenectomy. KEY WORDS: Axillary dissection ,Breast cancer, Sentinel Lymph Node Biopsy. PMID: 29051403 [PubMed - in process]
Authors: Yang X, Cheng Z, Zhang L, Wu G, Shi R, Gao Z, Li C Abstract A wealth of evidence suggests that proteins from prion protein (PrP) family contribute to tumorigenesis in many types of cancers, including pancreatic ductal adenocarcinoma (PDAC), breast cancer, glioblastoma, colorectal cancer, gastric cancer, melanoma, etc. It is well documented that PrP is a biomarker for PDAC, breast cancer, and gastric cancer. However, the underlying mechanisms remain unclear. The major reasons for cancer cell-caused patient death are metastasis and multiple drug resistance, both of which connect to physiological functions of...
Abstract Male breast cancer (MBC) accounts for 1% of all breast cancer. Adult obesity and tallness are risk factors for MBC, but the role of adolescent fatness is largely unknown. We aimed to assess the association between body mass index (BMI) in adolescence and the incidence of MBC in a large cohort of 16‐19 year‐old Israeli males. 1,382,093 Jewish Israeli males aged 16‐19 who underwent anthropometric measurements, a General Intelligence Test (GIT) and other examinations during 1967‐2011, were followed up to 31.12.2012 for MBC incidence. Cox proportional hazards models assessed the association between adolescent ...
Contributors : Qifeng Yang ; Ning ZhangSeries Type : Expression profiling by arrayOrganism : Homo sapiensSREBP1 is a master regulator of lipogenic gene expression. However, the underlying mechanisms of SREBP1-mediated metastasis has not been thoroughly elucidated.We involved microarray to analyze the differences of gene expression profiling between breast cancer cells with stable SREBP1 knockdown and the control cells.
Prevention and early detection of treatable medical conditions is an appealing concept. Preventive health care encompasses primary prevention of illness (eg, immunization against infectious disease or adoption of a healthy lifestyle), secondary prevention that involves early detection of latent disease (eg, colon and breast cancer screening), or tertiary prevention that aims to limit disability or improve function for an individual with an existing condition (eg, exercise rehabilitation in chronic lung disease).
ConclusionsLow quality evidence supports the use of GnRHa before and/or during chemotherapy to reduce the risk of POI and increase the probability of spontaneous pregnancy in the short term. Further high quality RCTs with more accurate assessment of ovarian reserve are needed to support any practical recommendation.
Abstract ObjectiveBreast cancer patients are associated with an increased risk for committing suicide. The purpose of this study is to study the trends in the incidence of suicide mortality and identify pertinent risk factors among patients with breast cancer. MethodsA retrospective examination of the Surveillance Epidemiology and End Results (SEER) database between years 1973 and 2013 was performed. ResultsOverall, 474,128 patients were identified of which 773 had committed suicide. There were no significant differences in the incidence of suicide mortality over the last three decades (1984‐1993: 0.14%, 1994‐2003: 0.1...
Publication date: November–December 2017 Source:Revista Española de Medicina Nuclear e Imagen Molecular (English Edition), Volume 36, Issue 6 Author(s): D. Villasboas-Rosciolesi, C. Pérez, L. Capdevila, F. Ramos, V. Valenti, J.R. Garcia
Black women’s breast cancer mortality is now 40 percent higher than white women’s.
Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C7MB00489C, PaperAndrea Polo, Chiara Nittoli, Anna Crispo, Teresa Langastro, Stefania Cocco, Lorella Severino, Michelino De Laurentiis, Gennaro Ciliberto, Maurizio Montella, Alfredo Budillon, Susan Costantini Endocrine disrupting chemicals (EDCs) are natural or synthetic exogenous substances affecting human health. Although present at low concentrations in the environment, they can cause a broad range of negative effects... The content of this RSS Feed (c) The Royal Society of Chemistry