Reversal of diffuse patchy pattern in lung perfusion scan in a case of severe pulmonary arterial hypertension
A diffuse patchy pattern in the perfusion scan of the lung is a hallmark of severe pulmonary arterial hypertension (PAH). However, the mechanisms of this unique pattern remain uncertain. We here present the case of a 19-year-old woman with severe PAH who demonstrated reversal of the diffuse patchy pattern with improvement of pulmonary blood flow within a month after upfront triple combination therapy. Our case is a first report showing reversibility of diffuse patchy pattern by a short-term treatment in severe PAH.
Source: Heart and Lung - Category: Intensive Care Authors: Yoshihiko Kodama, Kohtaro Abe, Kazuya Hosokawa, Kisho Ohtani, Michinobu Nagao, Yoshitaka Hirooka, Kenji Sunagawa Source Type: research