Common Antidepressants Linked to Higher Fracture Odds in Menopausal Women

Drugs like Celexa, Prozac could undermine bone, research suggests
Source: WebMD Health - Category: Consumer Health News Source Type: news

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Publication date: Available online 11 October 2019Source: The Journal of Steroid Biochemistry and Molecular BiologyAuthor(s): Tang Li, Wenfa Zhang, Sheng-Xiang LinAbstractIn spite of the significant progress of estrogen-dependent breast cancer (BC) treatment, aromatase inhibitor resistance is a major problem limiting the clinical benefit of this frontier endocrine-therapy. The aim of this study was to determine the differential expression of steroid-converting enzymes between tumor and adjacent normal tissues, as well as their correlation in modulating intratumoral steroid-hormone levels in post-menopausal estrogen-depende...
Source: The Journal of Steroid Biochemistry and Molecular Biology - Category: Biochemistry Source Type: research
AbstractLactobacilli are considered as the most important microorganisms in regulating immune system and maintaining vaginal health. The uses and benefits of Lactobacilli as probiotics, particularly the regulation of immune system, are dependent on the strain used and a comprehensive understanding of their effects on the host. Several factors have been identified in Lactobacilli that influence the immune response, such as exopolysaccharides and proteins. The current study was designed to investigate the serum immunoreactivity of healthy women against common vaginal Lactobacilli immunoreactive proteins. Three common vaginal...
Source: World Journal of Microbiology and Biotechnology - Category: Microbiology Source Type: research
AbstractPurposeVulvovaginal atrophy (VVA) is a commonly reported issue among breast cancer patients, and its aetiology is multifactorial. Treatment is difficult in these women, particularly because the use of oestrogens has traditionally been discouraged. Vaginal laser treatment has been reported to improve symptoms. We aimed to assess the impact on symptoms and sexual function of vaginal laser in women with early breast cancer (EBC).MethodsWe performed a single-arm investigator initiated pilot study of female EBC patients with symptomatic VVA. A total of 3 vaginal laser treatments were administered 4  weeks apart. Qu...
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research
ConclusionThese results suggest that MHT ameliorates the symptoms of PCOS by improving the dysregulation of ovarian steroids and steroidogenic enzymes in PCOS rats.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
Conclusion: The current study suggests that anisocytosis could be a contributing factor in thyroid dysfunction. PMID: 31599643 [PubMed - as supplied by publisher]
Source: Future Medicine: Biomarkers in Medicine - Category: Internal Medicine Tags: Biomark Med Source Type: research
Condition:   Skin Aging Interventions:   Drug: Trigonella foenum-graceum extract topical cream;   Other: Facial Wash;   Other: Sunscreen Cream;   Other: Placebo Sponsor:   Indonesia University Active, not recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Menopause Symptoms Intervention:   Device: Cooling Bolero Sponsors:   Englewood Hospital and Medical Center;   Nanohealth, Inc. Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Title: How Does Early Menopause Affect a Woman's Heart?Category: Health NewsCreated: 10/10/2019 12:00:00 AMLast Editorial Review: 10/11/2019 12:00:00 AM
Source: MedicineNet Menopause General - Category: Primary Care Source Type: news
To investigate the prevalence of cardiovascular disease (CVD) risk factors and assess the 10-year risk of CVD in non-menopausal and postmenopausal women with type 2 diabetes mellitus (T2DM).
Source: BMC Endocrine Disorders - Category: Endocrinology Authors: Tags: Research article Source Type: research
Waseem Abbas, Ranga Raju RaoIndian Journal of Cancer 2019 56(4):293-296Adjuvant ovarian suppression, on addition to chemotherapy, reduces the risk of breast cancer in pre-menopausal women after surgery and adjuvant hormonal therapy. Suppression of Ovarian Function Trial (SOFT) and Tamoxifen and Exemestane Trial (TEXT) showed greater benefit with exemestane in high risk females in comparison to Tamoxifen. Ovarian Function Suppression (OFS) and exemestane became the standard of care, with 30% patients experiencing grade 3 and more side effects. Much higher benefit was seen in high risk group. But there are concerns about inc...
Source: Indian Journal of Cancer - Category: Cancer & Oncology Authors: Source Type: research
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