Valvular Prostaglandins Are Elevated in Severe Human Aortic Valve Stenosis

CONCLUSIONS: Our comprehensive analysis of oxylipins in the human AV identified the inflammatory and osteogenic regulating prostanoids to be positively correlated with AVS severity. This elucidation of prostanoid dysregulation warrants further research into COX inhibition to mitigate AVS.PMID:38357817 | DOI:10.1161/ATVBAHA.123.320001
Source: Arteriosclerosis, Thrombosis and Vascular Biology - Category: Cardiology Authors: Source Type: research