Possible antiosteoporotic mechanism of Cicer arietinum extract in ovariectomized rats.

CONCLUSION: The ongoing study speculates that the CAE exerts its action through regulation of RANK/RANKL/OPG system. As, CAE not only promotes osteoblast differentiation, but also up-regulates OPG and downregulates RANKL secretion in osteoblasts, subsequently prevents bone loss and osteoporosis. PMID: 26097532 [PubMed - in process]

http://www.ncbi.nlm.nih.gov/pubmed/26097532?dopt=Abstract

Source: International Journal of Clinical and Experimental Pathology - June 26, 2015 Category: Pathology Authors: Fahmy SR, Soliman AM, Sayed AA, Marzouk M Tags: Int J Clin Exp Pathol Source Type: research