Enhanced circulating ILC2s accompany by upregulated MDSCs in patients with asthma.

In this study, we sought to determine whether MDSCs are also participation in immune imbalance and its relationship with ILC2s in asthma. The data showed that the circulatory ILC2s or MDSCs and their characteristic cytokines or transcription factors were significantly enhanced in asthmatic patients, as well as in chronic obstructive pulmonary disease (COPD) or respiratory viral infections (RVI). Meanwhile, a Th2-dominated phenotype was found in patients with asthma which closely related to the expression levels of ILC2s and MDSCs associated moleculars. These findings indicated that Th2 polarization was close related to synergistically increased ILC2s and MDSCs, it may allow to further the comprehension of the contribution of these cells to the inflammatory response involved in asthma or other respiratory tract inflammatory diseases, such as COPD and RVI, as well as to develop novel therapeutic strategies. PMID: 26097539 [PubMed - in process]
Source: International Journal of Clinical and Experimental Pathology - Category: Pathology Authors: Tags: Int J Clin Exp Pathol Source Type: research

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This report describes higher rates of death for persons aged ≥25 years with both asthma and chronic obstructive pulmonary disease in certain industries and occupations.
Source: CDC Morbidity and Mortality Weekly Report - Category: American Health Tags: Asthma Chronic Obstructive Pulmonary Disease (COPD) MMWR Morbidity & Mortality Weekly Report Occupational Safety Health Death Rates Source Type: news
AbstractAsthma and chronic obstructive pulmonary disease (COPD) are amongst the most common chronic diseases worldwide, and are largely preventable by improving the quality of the air we breathe. The most commonly deployed treatment, the metered dose inhaler (MDI), uses hydrofluorocarbon propellants, which are powerful greenhouse gases that contribute disproportionately to the climate crisis. Alternative treatment strategies are required if we are to avoid contributing to the worst effects of climate change. These strategies include promoting non-pharmacological therapies like smoking cessation and pulmonary rehabilitation...
Source: Pharmaceutical Medicine - Category: Drugs & Pharmacology Source Type: research
Conclusion: The prevalence of respiratory symptoms and corresponding diagnoses varied between and within the countries. The proportion reporting a diagnosis of obstructive airway disease among individuals with respiratory symptoms varied, indicating differences in diagnostic patterns both between areas and by sex. PMID: 32475292 [PubMed - as supplied by publisher]
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
Conclusions: Mindfulness interventions could increase psychological resources in situations related to asthma and COPD symptoms. More randomized control trials are needed. PMID: 32475186 [PubMed - as supplied by publisher]
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
Recent research found women with COPD and asthma—even those who have never smoked—are at a higher risk of developing rheumatoid arthritis...
Source: The Rheumatologist - Category: Rheumatology Authors: Tags: Conditions Rheumatoid Arthritis 2019 ACR/ARP Annual Meeting asthma chronic obstructive pulmonary disorder COPD lungs Source Type: research
CONCLUSION: The analyses provides a real world approach to the management of acute or chronic cough in various clinical conditions with pro- or antitussive agents while avoiding their misuse in empirical settings. PMID: 32469706 [PubMed - as supplied by publisher]
Source: Respiratory Care - Category: Respiratory Medicine Authors: Tags: Respir Med Source Type: research
CONCLUSION: On the basis of a broadly based research and participatory development process, a set of indicators has been developed that enables comprehensive evaluation of the regional quality of care of cross-indication, integrated care models focusing on common diseases. In order to be able to increasingly evaluate aspects of care coordination and patient orientation, health promotion as well as nursing, palliative and emergency care in the future, it would be helpful if routine data were collected or made accessible in these areas as well. PMID: 32467041 [PubMed - as supplied by publisher]
Source: Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen - Category: Health Management Tags: Z Evid Fortbild Qual Gesundhwes Source Type: research
REGRESSION OF THE NAVIER-STOKES EQUATION SOLUTIONS FOR PULMONARY AIRWAY FLOW USING NEURAL NETWORKS. Proc IEEE Int Symp Biomed Imaging. 2019 Apr;2019:1229-1233 Authors: de Los Ojos Araúzo D, Nardelli P, San José Estépar R Abstract Computerized fluid dynamics models of particle deposition in the human airways are used to characterize deposition patterns that enable the study of lung diseases like asthma and chronic obstructive pulmonary disease (COPD). Despite this fact, the influence of patient-specific geometry on the deposition efficiency and patterns is not well documented nor mo...
Source: Proceedings - International Symposium on Biomedical Imaging - Category: Radiology Tags: Proc IEEE Int Symp Biomed Imaging Source Type: research
We read with interest the recent editorial by Keeley et al. [1] on the timely topic of changing pressurised metered dose inhalers (pMDIs) to dry powder inhalers (DPIs) due to the much higher carbon footprint of pMDIs [2]. We agree with the authors that global warming cannot be tackled only by focusing on inhaler devices, but as long as we can provide safe and effective treatment to our patients, we cannot overlook environmental facts either. We feel that Keeley et al. [1] gave an unjustified negative impression on the performance of DPIs. They imply that DPIs are more expensive than pMDIs, that switching from pMDI to DPI l...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Original Articles: Correspondence Source Type: research
The digital respiratory health company says this deal and clearance now give it access to 90% of the U.S. asthma and COPD market.
Source: mobihealthnews - Category: Information Technology Source Type: news
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