Lovastatin Differentially Affects Neuronal Cholesterol and Amyloid-β Production in vivo and in vitro.

CONCLUSIONS: Lovastatin modifies the mevalonate pathway without affecting cholesterol levels in vivo and is able to reduce Aβ levels only in vitro.
PMID: 26096465 [PubMed - as supplied by publisher]

Source: CNS Neuroscience and Therapeutics - June 20, 2015 Category: Neuroscience Authors: Mendoza-Oliva A, Ferrera P, Fragoso-Medina J, Arias C Tags: CNS Neurosci Ther Source Type: research