Characterization of idiopathic esophagogastric junction outflow obstruction

Conclusions & InferencesPrimary EGJ outflow obstruction has an unclear clinical significance. A substantial part of patients has unrelated symptoms, spontaneous symptom relief, or no stasis. Treated patients showed a beneficial response to botox injections. A small proportion develops achalasia at follow‐up.

We describe a cohort of patients with EGJ outflow obstruction. We aimed for a better understanding of this rare disease and a more evidence‐based treatment. A substantial part of patients has no symptoms correlating to outflow obstruction or no stasis on barium esophagography. Treated patients showed a beneficial response to treatment with botox injections. A small part of patients develops achalasia.

Source: Neurogastroenterology and Motility - June 22, 2015 Category: Gastroenterology Authors: F. B. van Hoeij, A. J. P. M. Smout, A. J. Bredenoord Tags: Original Article Source Type: research