Improved prognostic stratification of patients with isocitrate dehydrogenase-mutant astrocytoma

In conclusion, CNS WHO grade, global DNA methylation status, andCDKN2A homozygous deletion are prognostic in patients with IDH-mutant astrocytoma. Combination of these parameters allows for improved prediction of outcome. These data aid in designing upcoming trials using IDH inhibitors.
Source: Acta Neuropathologica - Category: Neurology Source Type: research