Mayo Clinic and United Therapeutics Collaborate on Lung Restoration Center

JACKSONVILLE, Fla., and SILVER SPRING, Md. — Mayo Clinic in Jacksonville, Florida, and United Therapeutics Corporation (NASDAQ: UTHR) today announced a collaboration to build and operate a lung restoration center on the Mayo campus. The goal is to significantly increase the volume of lungs for transplantation by preserving and restoring selected marginal donor lungs, making them [...]
Source: News from Mayo Clinic - Category: Databases & Libraries Source Type: news

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Kevin Budding, Jessica van Setten, Eduard A. van de Graaf, Oliver A. van Rossum, Tineke Kardol-Hoefnagel, Johanna M. Kwakkel-van Erp, Erik-Jan D. Oudijk, C. Erik Hack, Henderikus G. Otten
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Despite advances in device technology and treatment strategies infection remains a major cause of adverse events (AE) in mechanical circulatory support (MCS) patients. To characterize the epidemiology of MCS infection we examined the type, location, and timing of infection in the International Society for Heart and Lung Transplantation Registry (ISHLT) for Mechanically Assisted Circulatory Support (IMACS) over 3 years, 2013-2015.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: Original Clinical Science Source Type: research
Specialized T cells in induced bronchus-associated lymphoid tissue regulate alloimmune responses in the lung allograft.
Source: Science Translational Medicine - Category: Biomedical Science Authors: Tags: Editors ' Choice Source Type: research
We read with great interest the review by Yanagawa et al, entitled Surgery for tumors of the heart,1 where the authors thoroughly review cardiac tumors classification, diagnosis sequence as well as the suggested method of treatment for the different kinds of tumors. The authors address sarcoma's as one of the rare malignant tumors and suggest a two-step surgical approach to sarcoma that involve the heart and lung.
Source: Seminars in Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: ADULT – Letter to the Editor Source Type: research
Zerina Nelson, four, of Mesa, Arizona, was diagnosed with Hermansky-Pudlak syndrome, a genetic condition characterized by albinism and vision considered legally blind
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Conditions:   Lung Transplant Rejection;   Antibody-mediated Rejection Interventions:   Drug: Belatacept;   Drug: Carfilzomib Sponsors:   Duke University;   Bristol-Myers Squibb Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
We present a case of endobronchial fusariosis following bilateral sequential lung transplantation for idiopathic pulmonary arterial hypertension in a 13 years old boy who was treated successfully with posaconazole and nebulized amphotericin B. We discuss the role of nebulized amphotericin B in treating invasive pulmonary fungal disease in children. To our knowledge, this is the first pediatric case of endobronchial fusariosis reported in the literature.
Source: Medical Mycology Case Reports - Category: Biology Source Type: research
Chronic lung allograft dysfunction or CLAD, encompasses a variety of phenotypes including both obstructive and restrictive phenotypes as detected by pulmonary function testing (PFTs), and has advanced the understanding of current clinical guidelines1-5. From the initial classification of chronic lung allograft rejection based primarily on pulmonary function testing, clinical guidelines now encompass CLAD phenotypes, presumed causes, characteristic imaging findings, and refinement of histopathological grades.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research
Abstract Ceftolozane-tazobactam (C/T) pharmacokinetics during extracorporeal membrane oxygenation (ECMO) has not been previously studied. In this work we report on the C/T plasmatic levels in a lung transplant (LTX) recipient during ECMO, treated with C/T (i.v., 2 g ceftolozane and 1 g tazobactam, every 8 hours]) for a Pseudomonas aeruginosa pulmonary infection. PMID: 30642936 [PubMed - as supplied by publisher]
Source: Antimicrobial Agents and Chemotherapy - Category: Microbiology Authors: Tags: Antimicrob Agents Chemother Source Type: research
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
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