Catheter-based intervention for pulmonary vein stenosis due to fibrosing mediastinitis: The mayo clinic experience

Conclusions We describe the largest reported case series of catheter-based intervention for PV stenosis in FM. Although catheter-based therapy improved hemodynamics, short-term vascular patency and patient symptoms, the rate of life-threatening complications, restenosis and mortality associated with these interventions was found to be high. Despite these associated risks, catheter-based intervention is the only palliative option available to improve quality of life in severely symptomatic patients with PV stenosis and FM. Patients with PV stenosis and FM (especially those with bilateral disease) have an overall poor prognosis in spite of undergoing these interventions due to the progressive and recalcitrant nature of the disease. This underscores the need for further innovative approaches to manage this disease.
Source: IJC Heart and Vasculature - Category: Cardiology Source Type: research