Sporogonic cycles based on degree-days for malaria parasite development in different eco-epidemiological settings in India.

Sporogonic cycles based on degree-days for malaria parasite development in different eco-epidemiological settings in India. Jpn J Infect Dis. 2015 Jun 12; Authors: Singh P, Dhiman RC Abstract Malaria transmission is prevalent in diverse geo-ecological paradigms in India. Temperature is one of the key determinants for transmission of malaria, causing low endemicity in some areas while intensified transmission in others. Using a degree-day model, we estimated maximum and minimum possible number of days necessary to complete a sporogonic cycle and possible number of Sporogonic cycles for Plasmodium vivax and Plasmodium falciparum in two different ecological settings with low and high endemicity for malaria at different elevations. In Raikhalkhatta (Himalayan foothills) not a single sporogonic cycle was possible from November to February while in Gandhonia village (forested hills), only one month was unsuitable. A minimum of 6 days and maximum of 46 days were required for completion of one sporogonic cycle. Forested hilly area was found more suitable for malaria parasites development in terms of sporogonic cycles (25 versus 21 for P falciparum and 32 versus 27 for P vivax). Degree days also provided the climatic explanation for the current transmission of malaria at different elevations. The calculation of degree-days and possible sporogonic cycles can be useful for their application in regional analysis of transmission dynamics and mana...
Source: Japanese Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Jpn J Infect Dis Source Type: research