Air Pollution Exposure during Pregnancy and Childhood Autistic Traits in Four European Population-Based Cohort Studies: The ESCAPE Project

Author Affiliations open 1Center for Research in Environmental Epidemiology, Barcelona, Spain; 2Pompeu Fabra University, Barcelona, Spain; 3Spanish Consortium for Research on Epidemiology and Public Health (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain; 4Department of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Centre–Sophia Children’s Hospital, Rotterdam, the Netherlands; 5The Generation R Study, Erasmus University Medical Centre, Rotterdam, the Netherlands; 6Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 7Department of Epidemiology Lazio Regional Health Service, Rome Italy; 8Inserm, Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, Grenoble, France; 9Grenoble University, Institut Albert Bonniot, Grenoble, France; 10Psychobiology area, Department of Basic Psychological Processes and Their Development, Faculty of Psychology, University of The Basque Country (UPV/EHU), Donostia-San Sebastian, Spain; 11Health Research Institute BIODONOSTIA, Donostia-San Sebastian, Spain; 12Institute for Risk Assessment Sciences, Utrecht University, Utrecht, the Netherlands;  13Centre for Environmental Policy, Imperial College London, London, UK; 14Foundation for the Promotion of Health and Biomedical Research in the Valencian Region, FISABIO-Public Health, Valencia, Spain; 15Department of Genes a...
Source: EHP Research - Category: Environmental Health Authors: Tags: Children's Health Source Type: research

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WEDNESDAY, Feb. 19, 2020 -- Young boys whose mothers were exposed to chemicals known as phthalates while pregnant may face an increased risk for developing behaviors associated with autism, a new study warns. Phthalates are chemicals found in many...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
Conclusion When analyzing the risk-benefit of folic acid supplementation at the recommended doses, 0.4 to 0.8 mg/day, it is concluded that the benefits outweigh the possible risks of developing ASD.
Source: Jornal Brasileiro de Psiquiatria - Category: Psychiatry Source Type: research
This study investigated whether antenatal exposure to antidepressants (ADs) increases the risks of autism spectrum disorders (ASD), attention deficit/hyperactivity disorders (ADHD), schizophrenia and other mental illnesses, and cognitive and developmental deficits in infants or preschool children. PubMed, EMBASE, BIREME/BVS databases were searched to identify studies examining associations of ADs in pregnancy with neurodevelopmental and psychiatric disorders. Twenty studies addressed ASD and/or ADHD risks while 30 focused on developmental and cognitive deficits in infants or preschool children. Most studies detected no ass...
Source: Cadernos de Saude Publica - Category: International Medicine & Public Health Authors: Tags: Cad Saude Publica Source Type: research
Alan Brown’s research links infections, chemical exposures, and inflammation in pregnancy to offspring’s schizophrenia, autism, and more. (read more)
Source: Environmental Factor - NIEHS Newsletter - Category: Environmental Health Source Type: news
Autism spectrum disorder is a neurodevelopmental disorder characterized by reduced social interactions, impaired communications, and stereotypic and repetitive behavior with different degrees of severity. The etiology of autism spectrum disorder is unknown, although the interaction of genetic and environmental factors is believed to play a fundamental role in the process. The main aim of this narrative review is to discuss the current knowledge about the interrelationships between vitamin D deficiency during pregnancy and autism spectrum disorder development. Literature analysis showed that vitamin D supplementation during...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Associations Between Broader Autism Phenotype and Dietary Intake: A Cross-Sectional Study (Japan Environment &Children's Study). J Autism Dev Disord. 2020 Jan 29;: Authors: Hirokawa K, Kimura T, Ikehara S, Honjo K, Ueda K, Sato T, Iso H, Japan Environment &Children’s Study Group Abstract The purpose of the present study was to investigate associations of dietary intake including vitamin D, folate, and n-3 and n-6 polyunsaturated fatty acids (PUFA) in pregnant women with broad autism phenotype (BAP). The Japan Environment and Children's Study is a government-funded birth cohort study. All...
Source: Journal of Autism and Developmental Disorders - Category: Psychiatry Authors: Tags: J Autism Dev Disord Source Type: research
Publication date: Available online 21 January 2020Source: Journal of Hazardous MaterialsAuthor(s): Tianyu Dong, Quanquan Guan, Weiyue Hu, Mingzhi Zhang, Yuqing Zhang, Minjian Chen, Xinru Wang, Yankai XiaAbstractGlufosinate ammonium (GLA) is a widely used organophosphate herbicide, which could be commonly detected in body fluids of both pregnant women and newborns. Existing evidences indicate that GLA has reproductive toxicity, while data concerning the effects of prenatal GLA exposure on neurodevelopment is rather limited. Here we employed a mouse model exposed to GLA prenatally. Reduced locomotor activity, impaired memory...
Source: Journal of Hazardous Materials - Category: Environmental Health Source Type: research
AbstractObjectiveTo evaluate the long-term pediatric neuropsychiatric morbidity of children born to obese patients.Study designA population-based cohort analysis was performed comparing all deliveries of obese (maternal pre-pregnancy body mass index of 30  kg/m2 or more) and non-obese patients between 1991 and 2014 at a single tertiary medical center. Hospitalizations of the offspring up to the age of 18  years involving neuropsychiatric morbidities were evaluated according to a pre-defined set of ICD-9 codes, including autistic, eating, sleeping and movement disorders, cerebral palsy, developmental disorders, an...
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
ConclusionsOur findings suggest that high maternal serum folate status during early pregnancy may be associated with the occurrence of ASD in offspring. No inference about physiological mechanisms behind this observation can be made at the present time because blood folate levels may have complex relations with nutritional intake, the cellular folate status and status of other B-vitamins. Therefore, further investigations, which may clarify the potential role and mechanisms of maternal blood folate status in ASD risk and the interplay with other potential risk factors, in larger materials are warranted.
Source: Molecular Autism - Category: Molecular Biology Source Type: research
(University of Cambridge) Autistic mothers are more likely to report post-natal depression compared to non-autistic mothers, according to a new study of mothers of autistic children carried out by researchers at the University of Cambridge. A better understanding of the experiences of autistic mothers during pregnancy and the post-natal period is critical to improving wellbeing.
Source: EurekAlert! - Social and Behavioral Science - Category: International Medicine & Public Health Source Type: news
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