[Correspondence] Livebirth after uterus transplantation

Mats Brännström and colleagues1 reported the first livebirth after uterus transplantation. The pregnancy was complicated by pre-eclampsia, resulting in preterm delivery. Immunosuppression, aged uterus, and assisted reproduction—individually or together—might explain development of pre-eclampsia. The patient had congenital absence of uterus and vagina associated with unilateral renal agenesis. Presence of only one kidney is thought to be a possible risk factor for pre-eclampsia in kidney donors. Gestational hypertension or pre-eclampsia are more likely to be diagnosed in kidney donors than in healthy non-donors.

Source: LANCET - June 12, 2015 Category: Journals (General) Authors: Pentti K Heinonen Tags: Correspondence Source Type: research