Biomarkers for Ilex pubescens under anti-platelet activity-oriented isolation

Publication date: August 2015 Source:Biochemical Systematics and Ecology, Volume 61 Author(s): Li-Ping Lin , Ying Li , Ji-Chao Zhang , Ye Lu In the present study, eleven ursane triterpenoids (1—11), seven oleanane triterpenoids (12—18), one lupine sapogenin (19) as well as two sterols (20 and 21) were obtained from Ilex pubescens under the anti-platelet activity-oriented isolation. Among them, compounds 2 and 4 were isolated from I. pubescens for the first time, while the isolation of the compounds 12, 15, 16 and 17 was a new finding in the Aquifoliaceae family. Our present study exhibited the taxonomic relationships (similarities and differences) between I. pubescens and some other species of genus Ilex. The result also suggested that triterpenoids are the anti-platelet components which may be fingerprints and serve as biomarkers for seeking alternative sources for I. pubescens.

Source: Biochemical Systematics and Ecology - June 10, 2015 Category: Biochemistry Source Type: research