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How To Mend A Broken Heart

(Photo: © Kyle Bean) The need to mend broken hearts has never been greater. But what if we could simply manufacture a new one? Alex O’Brien studies the legacy of Texan surgeons and artificial hearts.Haskell Karp was 37 when he suffered his first heart attack, and over the next ten years he suffered a variety of related problems. By 1969 even the slightest effort, like combing his hair or brushing his teeth, would bring on chest pain or extreme shortness of breath. There are four grades of heart failure under the classification determined in 1928 by the New York Heart Association; Karp’s was classified as grade IV, the most severe.The surgeon who treated him at St Luke’s Hospital, Texas, in 1969 was an energetic man called Denton Cooley. “The man had a big dilated heart and I hoped we could reduce the size of that heart, so it could regain some of its own function,” says Cooley. But Karp did not respond well to the treatment; half of his heart was beyond repair. Cooley had expected this. He’d discussed it with Karp before the surgery: “I don’t think your heart’s going to be strong enough to tolerate this operation,” he’d told him. But Cooley had made a suggestion: if Karp’s heart were to be too weak at the end of the operation, how about taking a replacement ­– an experimental artificial heart they’d been developing in the lab.The mechanical heart was a temporary ‘bridge&rsquo...
Source: Science - The Huffington Post - Category: Science Source Type: news

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Authors: Rafiq K Abstract Cardiovascular disease (CVD) is a class of diseases that involve disorders of heart and blood vessels, including: hypertension, coronary heart disease, cerebrovascular disease, peripheral vascular disease, which finally lead to heart failure (HF). There are several treatments available all over the world, but still CVD and heart failure became the number one problem causing death every year worldwide. Both experimental and clinical studies have shown a role for inflammation in the pathogenesis of heart failure. This seems related to an imbalance between pro-inflammatory and anti-inflammato...
Source: Cardiovascular and Hematological Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Cardiovasc Hematol Disord Drug Targets Source Type: research
Authors: Bussotti M, Marchese G Abstract The effects of hypoxia on the human organism has been considered doubly fascinating by the scientific community: the knowledge of the discrete mechanisms allowing the acclimatization both at the genetic level or through the cell mediators production in addition to the macroscopic responses of the cardio-circulatory and ventilatory systems to a hypoxic environment has been progressively developed since the last century; moreover granting a safer stay in hypoxic conditions not only for the residents but also for the different cathegories of workers, sportsmen and tourists has ...
Source: Cardiovascular and Hematological Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Cardiovasc Hematol Disord Drug Targets Source Type: research
Authors: Cho JC, Childs-Kean LM, Zmarlicka MT, Crotty MP Abstract Omadacycline is a novel aminomethylcycline antimicrobial agent that is available in both oral and intravenous formulations. The distinguishing structural characteristics of omadacycline from other tetracyclines allow for its continued antimicrobial activity in the presence of traditional tetracycline resistance mechanisms (efflux pumps and ribosomal protection proteins). Omadacycline has been found to have potent activity against antibiotic-resistant pathogens including methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus, e...
Source: Drugs of Today - Category: Drugs & Pharmacology Tags: Drugs Today (Barc) Source Type: research
CONCLUSION: Inserting a smaller sized peripheral intravenous catheter did not result in a lower pain sensation. Moreover, to prevent pain upon inserting a peripheral intravenous catheter, an unsuccessful attempt must be avoided. PMID: 29772984 [PubMed - in process]
Source: The Journal of Vascular Access - Category: Surgery Tags: J Vasc Access Source Type: research
CONCLUSION: Decreased burden of illness related to cannulation (less infiltrations during hemodialysis) and Qb were associated with plastic cannulae. Decreased procedure costs were suggested during the study period in the plastic group. PMID: 29772982 [PubMed - in process]
Source: The Journal of Vascular Access - Category: Surgery Tags: J Vasc Access Source Type: research
The objective of the present study was to assess the possible utility of the difference in coronary sinus diameter to quantify stable atherosclerotic plaque(s) using 256-slice coronary computed tomographic angiography. MATERIAL AND METHODS A total of 336 patients were divided into 2 groups with 168 patients each. Patients who had heart failure were included in the study group and those who did not were included in the non-study group. Patients were subjected to cross-sectional study. Cardiovascular images were performed with 256-slice coronary computed tomographic angiography with a prospective electrocardiogram and clinic...
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
A modern blend of yoga, Zen Buddhism, hypnosis and psychology, it ’s huge on the continent and it’s on its way hereMindfulness is the tried-and-tested tool of our times for anxiety, depression, chronic pain, addiction and more, but what if it ’s not your thing? For those too twitchy to sit still and focus on breathing, the ubiquitous mindfulness apps, self-help sheets and courses in schools and workplaces are little more than totems of uselessness. But you wouldn’t have this problem if you lived in France, Italy, Spain, Switzerland o r Portugal, because you’d be doing sophrology instead. It&rs...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Life and style Psychology Science Health & wellbeing Source Type: news
BOWEL cancer symptoms include stomach pain, a change in bowel habits, and finding blood in your stool. You could reveal your risk of the cancer by checking your poo after using the toilet. Should a healthy poo sink or float?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
This is a fishy recommendation from the AHA. And here's the type of fish that's better for your heart.
Source: Forbes.com Healthcare News - Category: Pharmaceuticals Authors: Source Type: news
When pain settled into Blair Golson's hands, it didn't let go.What started off as light throbbing in one wrist 10 years ago quickly engulfed the other. The discomfort then spread, producing a pain much"like slapping your hands against a concrete wall," he says. He was constantly stretching them, constantly shaking them, while looking for hot or cold surfaces to lay them on for relief.But worse was the deep sense of catastrophe that accompanied the pain. Working in tech-related startups, he depended on his hands to type."Every time the pain got bad, I would think some variation of,'Oh no, I'm ...
Source: Psychology of Pain - Category: Anesthesiology Source Type: blogs
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