Comparison of haploidentical stem cell transplantation with post-transplant cyclophosphamide versus umbilical cord blood transplantation in adult patients with aplastic anemia

Aplastic anemia is a bone marrow (BM) failure disorder that may lead to life-threatening complications, such as infection and bleeding, if hematopoiesis is not restored through treatment. Allogeneic hematopoietic stem cell transplantation (HSCT) from an alternative donor is an important treatment option for patients with immunosuppressive therapy (IST)-refractory aplastic anemia when an HLA-matched donor is not available1-3.

Source: Biology of Blood and Marrow Transplantation - September 18, 2023 Category: Hematology Authors: Yasushi Onishi, Takehiko Mori, Hirohito Yamazaki, Nobuhiro Hiramoto, Yoshitaka Zaimoku, Minoru Kanaya, Kosei Matsue, Makoto Onizuka, Nobuyuki Aotsuka, Naoyuki Uchida, Koichi Onodera, Junya Kanda, Hirohisa Nakamae, Ryusuke Yamamoto, Takuro Kuriyama, Takafu Source Type: research