Perceptions and Behavioral Responses of the General Public During the 2009 Influenza A (H1N1) Pandemic: A Systematic Review

Review Articles Marloes Bults, Desirée J.M.A. Beaujean, Jan Hendrik Richardus, Hélène A.C.M. Voeten, Disaster Medicine and Public Health Preparedness, Volume 9 Issue 02, pp 207-219Abstract
Source: Disaster Medicine and Public Health Preparedness - Category: Global & Universal Source Type: research

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Source: Browsing - Category: Databases & Libraries Tags: midwifery Source Type: blogs
Conclusions: The clinical features and outcomes of pandemic (H1N1) 2009 influenza and current circulating seasonal influenza A strains were comparable in hospitalised patients. However, since both seasonal and pandemic influenza can lead to significant morbidity and mortality, the impact of pre-existing seasonal influenza should not be underestimated during the pandemic period. PMID: 31304711 [PubMed - in process]
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
After the initial identification of the H1N1 pandemic influenza strain in Mexico in April 2009 and its subsequent global spread, several monovalent influenza vaccines were developed as part of the pandemic response. Three of these vaccines, Pandemrix, Arepanrix and Focetria were adjuvanted. One of these, the AS03-adjuvanted Pandemrix vaccine, was primarily used in Europe. Following widespread Pandemrix vaccine administration in Scandinavia, an increased risk of narcolepsy was noted in observational studies. Subsequently, this increased risk was also reported in other European countries as well. In contrast, studies from Ca...
Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: Vaccine Reports Source Type: research
Contributors : R E Drury ; D O'Connor ; A PollardSeries Type : Non-coding RNA profiling by arrayOrganism : Homo sapiensTo describe vaccine associated changes in the expression of microRNAs 21 days after vaccination in children receiving one of two pandemic influenza (H1N1) vaccines.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Non-coding RNA profiling by array Homo sapiens Source Type: research
In the twenty-first century, severe acute respiratory syndrome (SARS), 2009 A(H1N1) influenza, and Ebola have all placed strains on critical care systems. In addition to the increased patient needs common to many disasters, epidemics may further degrade ICU capability when staff members fall ill, including in the course of direct patient care. In a large-scale pandemic, shortages of equipment and medications can further limit an ICU ’s ability to provide the normal standard of care. Hospital preparedness for epidemics must include strategies to maintain staff safety, secure adequate supplies, and have plans for triag...
Source: Critical Care Clinics - Category: Intensive Care Authors: Source Type: research
THURSDAY, July 11, 2019 -- Exposure to the 2009 pandemic H1N1 (pH1N1) influenza vaccine in pregnancy is not associated with most negative health outcomes among offspring, according to a study published online July 10 in The BMJ. Laura K. Walsh, from...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
Source: BMJ - Category: General Medicine Source Type: research
The use of a good vaccine adjuvant may induce the higher immunogenicity profile of vaccine antigens. Here, we developed a new adjuvant by combining poly-γ-glutamic acid (γ-PGA) with alum (PGA/Alum), and investigated its ability to enhance the immunogenicity and the cross-reactive efficacy of pandemic H1N1 (pH1N1) influenza vaccine antigen. PGA/Alum enhanced antigen delivery to draining lymph nodes and antigen-specific immunogenicity in mice using OVA as a model antigen. It also greatly increased OVA-specific antibody production, cytotoxic T lymphocyte (CTL) activity, and antibody-dependent cellular cytotoxicity...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Abstract Avian influenza virus (AIV) is an extraordinarily diverse pathogen that causes significant morbidity in domesticated poultry populations and threatens human life with looming pandemic potential. Controlling avian influenza in susceptible populations requires highly effective, economical and broadly reactive vaccines. Several AIV vaccines have proven insufficient despite their wide use, and better technologies are needed to improve their immunogenicity and broaden effectiveness. Previously, we developed a "mosaic" H5 subtype hemagglutinin (HA) AIV vaccine and demonstrated its broad protection aga...
Source: Vaccine - Category: Allergy & Immunology Authors: Tags: Vaccine Source Type: research
We describe how CD8+ CTL memory is established following influenza virus infection, and how a robust CTL recall response can lead to more rapid virus elimination by destroying virus-infected cells, and recovery. Exploiting long-term, cross-reactive CTL against the continuously evolving and unpredictable influenza viruses provides a possible mechanism for preventing a disastrous pandemic comparable to the 1918-1919 H1N1 “Spanish flu”, which killed more than 50 million people worldwide.
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
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