Antifungal compounds that evade resistance reported in Nature Chemistry Biology

(Pure Communications Inc.) Antifungal drug discovery progress was reported by the founder of REVOLUTION Medicines founder. Molecules derived from natural product amphotericin B, used as a highly effective treatment for serious fungal infections but is often accompanied by serious side effects, were active against fungal pathogens that cause life-threatening human diseases, effective in treating a rodent model of systemic yeast infections, significantly less toxic to human cells, and unlike many antifungals used today, evaded emergence of drug resistance.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news