Pediatric Vaccines and Neurodevelopment: Primate Study Finds No Adverse Behavioral Effects

Julia R. Barrett, MS, ELS, a Madison, WI–based science writer and editor, is a member of the National Association of Science Writers and the Board of Editors in the Life Sciences. About This Article open Citation: Barrett JR. 2015. Pediatric vaccines and neurodevelopment: primate study finds no adverse behavioral effects. Environ Health Perspect 123:A156; http://dx.doi.org/10.1289/ehp.123-A156 News Topics: Infectious Disease, Mental Health, Mercury, Neurologic Health Published: 1 June 2015 PDF Version (320 KB) Related EHP Article Examination of the Safety of Pediatric Vaccine Schedules in a Non-Human Primate Model: Assessments of Neurodevelopment, Learning, and Social Behavior Britni Curtis, Noelle Liberato, Megan Rulien, Kelly Morrisroe, Caroline Kenney, Vernon Yutuc, Clayton Ferrier, C. Nathan Marti, Dorothy Mandell, Thomas M. Burbacher, Gene P. Sackett, and Laura Hewitson Vaccination has successfully reduced the incidence and prevalence of many infectious diseases. However, in the absence of outbreaks, a perception has developed that vaccinations themselves may present a greater risk than the diseases they prevent.1 Although evaluations of the existing data have failed to identify links between vaccination and negative health outcomes,2,3 there remain some public concerns about a potential link with autism spectrum disorders. These concerns are primarily due to the expansion of the infant immunization schedule and exposure to thimerosal, once used as...
Source: EHP Research - Category: Environmental Health Authors: Tags: Featured News Science Selection Infectious Disease June 2015 Mental Health Mercury Neurologic Health Source Type: research

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Authors: Siqueira-Batista R, De Souza Bayão T, Do Carmo Cupertino M, Alfred Joseph Mayers N, Patrícia Gomes A Abstract Yellow fever is an acute febrile illness for which there is no specific antiviral treatment. Since 2016, Brazil has experienced two outbreaks, and collective health measures have been adopted to contain these grievances. However, published data about the drug sofosbuvir against flaviviruses are promising, suggesting the relevance of conducting future clinical trials. PMID: 31613184 [PubMed - as supplied by publisher]
Source: Pathogens and Global Health - Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research
Experts in immunology, vaccine biology, biomedical engineering, optics and physics will use cutting-edge imaging technologies to watch the immune system work in real time and explore ways to better fight infections like the flu.
Source: University of Rochester Medical Center Press Releases - Category: Universities & Medical Training Authors: Source Type: news
AbstractPurposeTo determine the diagnostic performance of intravoxel incoherent motion (IVIM) parameters to predict tumor recurrence after hepatectomy in patients with hepatitis B virus (HBV) –related hepatocellular carcinoma (HCC).Materials and methodsOne hundred and fifty-seven patients (mean age 52.54  ± 11.32 years, 87% male) with surgically and pathologically confirmed HCC were included. Regions of interests were drawn including the tumors by two independent radiologists. ADC and IVIM-derived parameters (true diffusion coefficient [D]; pseudodiffusion coefficient [D*]; pseudodiffusion f...
Source: European Radiology - Category: Radiology Source Type: research
Authors: Liu N, Feng J, Lv Y, Liu Q, Deng J, Xia Y, Guo C, Zhou Y Abstract The accumulation of toxic bile acids (BAs) is closely related to liver injury, inflammation and tumorigenesis. The aim of the present study was to determine the role of the serum BA spectrum in the diagnosis and progression of liver cirrhosis. This was a prospective observational study involving patients with chronic hepatitis (n=23), liver cirrhosis (n=101), and cirrhosis complicated with hepatocellular carcinoma (CC-HCC; n=56). The 6-month survival of cirrhotic patients was recorded after blood collection. Comparisons of serum total BAs an...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Authors: Pu F, Feng J, Yang L, Zhang L, Xia P Abstract Compared to other diseases, early or atypical spinal tuberculosis (TB) is prone to being misdiagnosed due to the lack of specific clinical manifestations and misleading negative results of various laboratory analyses and imaging examinations. Various methods for diagnosing spinal TB have become research hotspots. Recently, it has been proposed that effective vaccination is a mainstay of long-term policies to combat and control the TB epidemic. However, some new TB vaccines require further evaluation and clinical trials to demonstrate their efficiency and safety...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Authors: Bronstein FN, Meyer B, Condat B, Loria A, Bronstein JA PMID: 31611136 [PubMed - as supplied by publisher]
Source: Medecine et Maladies Infectieuses - Category: Infectious Diseases Tags: Med Mal Infect Source Type: research
Authors: Goullé JP, Grangeot-Keros L Abstract French people have never been so wary about vaccines. The use of aluminum salts in vaccine adjuvants to enhance effectiveness is one of the major reasons for this lack of confidence. The direct toxicity of aluminum is often put forward. Direct toxicity of aluminum has long been known-especially with occupational exposure-to be associated with characteristic clinical manifestations and increased blood aluminum level. Intoxication related to the excessive amount of an element in the body, whether be it lead poisoning following exposure to lead or mercury poisoning ...
Source: Medecine et Maladies Infectieuses - Category: Infectious Diseases Tags: Med Mal Infect Source Type: research
Publication date: Available online 16 October 2019Source: Journal of the Formosan Medical AssociationAuthor(s): Shih-Jer Hsu, Sheng-Shun Yang, Jia-Horng KaoAlthough interferon (IFN)-based therapy has been shown to reduce hepatocellular carcinoma (HCC) development once patients with chronic hepatitis C virus (HCV) infection achieve sustained virologic response (SVR), IFN-based therapy is limited by its multiple adverse effects, non-oral administration, and unsatisfactory SVR rate. In recent years, IFN-free all-oral direct-acting antivirals (DAAs) have replaced IFN-based therapy as the standard of care for HCV infection worl...
Source: Journal of the Formosan Medical Association - Category: General Medicine Source Type: research
Publication date: Available online 15 October 2019Source: IDCasesAuthor(s): Lazara Karelia Montane Jaime, Patrick E. Akpaka, Sehlule Vuma, Angel A Justiz-VaillantAbstractA 56-year-old woman who vaccinated as a child with the Bacillus Calmette-Guerin (BCG), now tests positive to the tuberculin skin test (TST) but test negative to the Quantiferon Gold assay. She has no history of tuberculosis contact and is asymptomatic. This dilemma now is, should be treated for tuberculosis or not, based only on the TST results? To prevent these false positive results with TST and avoid treatment with isoniazid (INH) it may be helpful to u...
Source: IDCases - Category: Infectious Diseases Source Type: research
Publication date: Available online 15 October 2019Source: IDCasesAuthor(s): Garyfallia Syridou, Ioannis Drikos, Artemis Vintila, Antigoni Pegkou, Loukia Zografou, Panagiotis Roungas, Eleni Papa, Dimitris Kyriazopoulos, Olga Savelieva, Antonopoulou EleniAbstractInfluenza virus primarily affects the respiratory system. It rarely causes extrapulmonary complications, with otitis media and febrile seizures being the most common in children. Acute glomerulonephritis as a complication of H1N1 influenza virus infection has been described only sporadically.Herein we present a case of acute glomerulonephritis in a previously healthy...
Source: IDCases - Category: Infectious Diseases Source Type: research
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