A pathogenetic role for IL-21 in primary Sjögren syndrome

Nature Reviews Rheumatology 11, 368 (2015).
doi:10.1038/nrrheum.2014.225

Authors: Seung-Ki Kwok, Jennifer Lee, Di Yu, Kwi Young Kang, Mi-La Cho, Hae-Rim Kim, Ji Hyeon Ju, Sang-Heon Lee, Sung-Hwan Park & Ho-Youn Kim
Advances in our understanding of the pathogenesis of primary Sjögren syndrome (pSS) characterize it as a highly complex process encompassing both the initiation of innate immunity and subsequent adaptive immune responses. IL-21 is receiving attention as a potential key player in the pathogenesis of pSS

Source: Nature Reviews Rheumatology - January 13, 2015 Category: Rheumatology Authors: Seung-Ki KwokJennifer LeeDi YuKwi Young KangMi-La ChoHae-Rim KimJi Hyeon JuSang-Heon LeeSung-Hwan ParkHo-Youn Kim Tags: Perspectives Source Type: research