Extreme volume expansion of a vestibular schwannoma due to intratumoral hemorrhage after gamma knife radiosurgery

Publication date: July 2015 Source:Journal of Clinical Neuroscience, Volume 22, Issue 7 Author(s): Shunichiro Miki , Eiichi Ishikawa , Tetsuya Yamamoto , Hiroyoshi Akutsu , Masahide Matsuda , Noriaki Sakamoto , Akira Matsumura A 48-year-old man with right hemi-facial palsy and cerebellar ataxia was referred to our hospital. Three years and 10months earlier he had undergone gamma knife radiosurgery (GKRS) at the referring hospital for an 18mm right vestibular schwannoma. Slight tumor enlargement had been observed on MRI performed at the referring hospital 3years after the GKRS. On close follow-up after another 6months an MRI showed an obvious enlargement of the tumor. An MRI on admission revealed an iso-intense mass lesion measuring 36mm in maximum diameter at the right cerebellopontine angle. A two stage surgery was conducted using a retrosigmoid approach because bleeding from the tumor wall was difficult to control intraoperatively during the first operation. At the second operation, the majority of the tumor capsule had converted to necrotic tissue. A large hematoma cavity was present inside the tumor capsule which explained the rapid increase in size over a short period of time. Near total removal was achieved. Histopathological examination revealed massive intratumoral hemorrhage within a typical vestibular schwannoma with no malignancy. The complication of intratumoral hemorrhage is very rare and the utility of stereotactic radiation surgery/therapy, including GKRS, fo...
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research

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Source: Journal of the International Academy of Periodontology - Category: Dentistry Tags: J Int Acad Periodontol Source Type: research
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Source: Journal of the International Academy of Periodontology - Category: Dentistry Tags: J Int Acad Periodontol Source Type: research
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Source: Surgical Endoscopy - Category: Surgery Source Type: research
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Source: Drugs.com - New Drug Approvals - Category: Drugs & Pharmacology Source Type: news
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Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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Source: Hellenic Journal of Nuclear Medicine - Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research
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Source: Scandinavian Journal of Urology - Category: Urology & Nephrology Tags: Scand J Urol Source Type: research
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