Epidemiology of Barrett's Esophagus and Esophageal Adenocarcinoma.

Epidemiology of Barrett's Esophagus and Esophageal Adenocarcinoma. Gastroenterol Clin North Am. 2015 Jun;44(2):203-231 Authors: Runge TM, Abrams JA, Shaheen NJ Abstract Barrett's esophagus (BE) is the precursor to esophageal adenocarcinoma (EAC), a disease with increasing burden in the Western world, especially in white men. Risk factors for BE include obesity, tobacco smoking, and gastroesophageal reflux disease (GERD). EAC is the most common form of esophageal cancer in the United States. Risk factors include GERD, tobacco smoking, and obesity, whereas nonsteroidal antiinflammatory drugs and statins may be protective. Factors predicting progression from nondysplastic BE to EAC include dysplastic changes on esophageal histology and length of the involved BE segment. Biomarkers have shown promise, but none are approved for clinical use. PMID: 26021191 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/26021191?dopt=Abstract

Source: The Medical Clinics of North America - May 31, 2015 Category: Journals (General) Authors: Runge TM, Abrams JA, Shaheen NJ Tags: Gastroenterol Clin North Am Source Type: research