Plasmablastic Lymphoma: Past, Present, and Future

Clin Lymphoma Myeloma Leuk. 2023 Jun 14:S2152-2650(23)00181-7. doi: 10.1016/j.clml.2023.05.014. Online ahead of print.ABSTRACTPlasmablastic Lymphoma is a rare large B-cell lymphoma with unique immunohistochemical and morphological features. It was most commonly associated with HIV infection; however, it's now seen in other immunosuppressed states like autoimmune conditions, post-transplant settings, and even in elderly immunocompetent individuals. Although rare, it is an aggressive lymphoma with unfavorable outcomes. The aim of this manuscript is to have an in-depth review of the current knowledge of epidemiology, pathophysiology, prognostic markers, and treatment approaches currently in use and in clinical trials for this challenging disease.PMID:37453866 | DOI:10.1016/j.clml.2023.05.014
Source: Clinical Lymphoma and Myeloma - Category: Cancer & Oncology Authors: Source Type: research