Direct thrombin inhibitor – Cardiology MCQ

Which of the following is a direct thrombin inhibitor? a) Apixaban b) Rivaroxaban c) Dabigatran d) Acenocoumarol Correct answer: c) Dabigatran Apixaban and rivaroxaban are direct factor Xa inhibitors, while acenocoumarol is a vitamin K antagonist. First three are newer oral anticoagulants while acenocoumarol has been in use for decades. Therapeutic effect of acenocoumarol can be monitored with prothrombin time while those of the newer anticoagulants cannot be monitored using widely available tests. Similarly effect of acenocoumarol can be reversed by vitamin K while a direct antidote is not available for the newer oral anticoagulants, though their safety profile has been shown to be good and therapeutic effects more predictable than that of vitamin K antagonists. The post Direct thrombin inhibitor – Cardiology MCQ appeared first on Cardiophile MD.
Source: Cardiophile MD - Category: Cardiology Authors: Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs