Modulation of lncRNA links endothelial glycocalyx to vascular dysfunction of tyrosine kinase inhibitor

CONCLUSIONS: Our findings highlight the importance of lncRNA-mediated regulation of the endothelial glycocalyx as an important determinant of sunitinib-induced vascular toxicity and reveal potential novel therapeutic avenues to attenuate sunitinib-induced vascular dysfunction.PMID:37267414 | DOI:10.1093/cvr/cvad087

Source: Cell Research - June 2, 2023 Category: Cytology Authors: Sarath Babu Nukala Jordan Jousma Gege Yan Zhenbo Han Youjeong Kwon Yoonje Cho Chuyu Liu Keith Gagnon Sandra Pinho Jalees Rehman Ning-Yi Shao Sang-Bing Ong Won Hee Lee Sang-Ging Ong Source Type: research