Peroxynitrite Decomposition Catalyst Reduces Delayed Thrombolysis-induced Hemorrhagic Transformation in Ischemia-reperfused Rat Brains.

CONCLUSION: Peroxynitrite decomposition catalyst could prevent hemorrhagic transformation and improve neurological outcome ischemic rat brains with delayed t-PA treatment via inhibiting peroxynitrite-mediated MMP activation. PMID: 25996167 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/25996167?dopt=Abstract

Source: CNS Neuroscience and Therapeutics - May 21, 2015 Category: Neuroscience Authors: Chen HS, Chen XM, Feng JH, Liu KJ, Qi SH, Shen JG Tags: CNS Neurosci Ther Source Type: research