Monoclonal gammopathies of renal significance

Clin Med (Lond). 2023 May;23(3):250-253. doi: 10.7861/clinmed.2023-RM3.ABSTRACTThe term monoclonal gammopathies of renal significance (MGRS) encompasses a group of renal histopathological lesions fulfilling two criteria: (a) they are caused by nephrotoxic monoclonal immunoglobulins and (b) the monoclonal immunoglobulins are produced by small B-cell or plasma cell clones which do not meet the criteria for multiple myeloma or malignant lymphoma. Here, we provide a review of the MGRS definition and related terminology and elaborate on the diagnostic approach and treatment principles from the general physician perspective.PMID:37236803 | DOI:10.7861/clinmed.2023-RM3
Source: Clinical Lymphoma and Myeloma - Category: Cancer & Oncology Authors: Source Type: research