Flucloxacillin is a weak inducer of CYP3A4 in healthy adults and 3D spheroid of primary human hepatocytes

In conclusion, flucloxacillin is a weak inducer of CYP3A4, which may lead to clinically relevant drug-drug interactions for some narrow therapeutic range drugs that are substrates of CYP3A4.PMID:37235733 | DOI:10.1002/cpt.2959

Source: Clinical Pharmacology and Therapeutics - May 26, 2023 Category: Drugs & Pharmacology Authors: Ditte B Iversen Ann-Cathrine Dalg ård Dunvald Daniel M Jespersen Flemming Nielsen Kim Br øsen Per Damkier Helen S Hammer Oliver P ötz Erkka J ärvinen Tore B Stage Source Type: research