A preliminary X-ray study of 3-deoxy-d-manno-oct-2-ulosonic acid 8-phosphate phosphatase (YrbI) from Burkholderia pseudomallei

In this study, YrbI from Burkholderia pseudomallei, the causative agent of melioidosis, has been cloned, expressed, purified and crystallized. Synchrotron X-ray data were also collected to 2.25 Å resolution. The crystal belonged to the primitive orthorhombic space group P212121, with unit-cell parameters a = 63.7, b = 97.5, c = 98.0 Å. A full structural determination is in progress to elucidate the structure–function relationship of this protein.
Source: Acta Crystallographica Section F - Category: Biochemistry Authors: Tags: 3-deoxy-d-manno-oct-2-ulosonic acid 8-phosphate phosphatase YrbI Burkholderia pseudomallei research communications Source Type: research