Toward standardization of tau PET imaging corresponding to various tau PET tracers: a multicenter phantom study

ConclusionsThe phantom activity was comprehensive for first- and second-generation tau PET tracers. The mid-range activity that we determined could be applied to later tau PET tracers. We propose an analytical tau-specific VOI template based on tau pathophysiological changes in patients with AD to standardize tau PET imaging. Phantom images reconstructed under the optimized conditions for tau PET imaging achieved excellent image quality and quantitative accuracy.
Source: Annals of Nuclear Medicine - Category: Nuclear Medicine Source Type: research