Vascular endothelial growth factor (-460 C/T, +405 G/C, and +936 C/T) polymorphisms and endometriosis risk in Tunisian population.

This study includes 105 women with endometriosis and 150 women with no laparoscopic evidence of disease. Genotyping of the VEGF -460 C/T, +405 G/C, and +936 C/T polymorphisms were performed by polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP). The distribution of genotypes (P = 0.006) and allele (P = 0.0009) frequencies of the +936 C/T polymorphism was significantly different between patients and controls. Patients with stages III-IV endometriosis showed a higher VEGF + 936T allele frequency than controls (P = 0.0001). However, the distribution of genotypes and allele frequencies of the VEGF -460 C/T and +405 G/C polymorphisms did not differ significantly between endometriosis patients and controls. These findings suggest that the VEGF +936 C/T polymorphism may be a risk factor for endometriosis development and the VEGF +936 T allele is associated with an increased risk of stages III-IV endometriosis in the Tunisian population. PMID: 25984730 [PubMed - as supplied by publisher]
Source: Systems Biology in Reproductive Medicine - Category: Reproduction Medicine Authors: Tags: Syst Biol Reprod Med Source Type: research

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The purpose of this video is to describe the vaginal appendectomy (VagAppy), a novel approach to coincidental appendectomy at time of hysterectomy. Coincidental appendectomy at time of a primary gynecologic procedure has been described in the literature for many years. There is a growing body of evidence supporting appendectomy as part of surgical management of endometriosis given the prevalence of appendiceal endometriosis, as high as 39% in deep infiltrating endometriosis. A common technique for performance of a laparoscopic appendectomy is with a surgical stapler.
Source: American Journal of Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Video Cafe Source Type: research
ConclusionsIn women affected by recto ‐vaginal endometriosis with vaginal mucosal infiltration, perioperative outcomes seem not to be influenced by the surgical route adopted.
Source: Acta Obstetricia et Gynecologica Scandinavica - Category: OBGYN Authors: Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
Authors: Sachedina A, Todd N Abstract Most adolescents will experience discomfort during menstruation. Due to normalization of dysmenorrhea, there is delay to diagnosis and treatment. Non-steroidal anti-inflammatories are a first line treatment. Adolescents can safely be offered menstrual suppression with combined hormonal contraception, and progestin-only options. When the above are ineffective, gonadotropin releasing hormone agonists with add back treatment can be considered. Transabdominal ultrasound is indicated when first line treatments do not improve symptoms. Endometriosis should be considered in adolescent...
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - Category: Endocrinology Tags: J Clin Res Pediatr Endocrinol Source Type: research
ConclusionsIn women affected by recto ‐vaginal endometriosis with vaginal mucosal infiltration, perioperative outcomes seem not to be influenced by the surgical route adopted.
Source: Acta Obstetricia et Gynecologica Scandinavica - Category: OBGYN Authors: Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
Conclusion: Exposure to bisphenols may increase the risk of endometriosis, and oxidative stress may play a crucial role in this association. Further studies are warranted to verify these findings.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
Discussion of Use, Criteria and Advantages: a Review of the Literature. Acta Medica (Hradec Kralove). 2019;62(4):147-149 Authors: Gkegkes ID, Iavazzo C, Iatrakis G, Iavazzo PE, Pechlivani F, Antoniou E, Bakalianou K Abstract Endometriosis is a very common benign condition affecting fertility and quality of life. Different methods, either definitive or fertility sparing are used for its management by using open, laparoscopic, and robotic techniques. This is a literature review presenting the role and the advantages of robotic surgery in endometriosis. Such a management is effective, safe, and feasible i...
Source: Acta Medica: Hradec Kralove - Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research
Conclusions Our results indicate that ICG can identify the relevant pelvic nodes independent of tumor size, provided bilateral detection is achieved and additional, related diseases are excluded.Trial RegistrationThis trial is registered within the German Clinical Trial Register (DRKS-ID: DRKS00014692).
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
ConclusionFrozen pelvis is a situation where anatomy is distorted. The surgeon should find anatomical landmark in order to restore anatomy and to establish specific strategies adapted to the patient.
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
ConclusionThe mural fibrosis seen in the cystic wall reflects unrecognized ovarian stromal fibrosis induced by the fibrogenic effects of endometriosis. This process may play a potential role in provoking infertility in patients with endometriosis, and could be reversed by administrating the LH-inhibiting regimens.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
To describe a ten steps strategy to treat a severe endometriosis with a frozen pelvis by laparoscopy
Source: The Journal of Minimally Invasive Gynecology - Category: OBGYN Authors: Tags: Video Article Source Type: research
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