Journal update monthly top five

This month’s update is by the South East Scotland team. We used a multimodal search strategy, drawing on free open-access medical education resources and literature searches. We identified the five most interesting and relevant papers (decided by consensus) and highlight the main findings, key limitations and clinical bottom line for each paper. The papers are ranked as: Worth a peek—interesting, but not yet ready for prime time. Head turner—new concepts. Game changer—this paper could/should change practice. Early Restrictive or Liberal Fluid Management for Sepsis-Induced Hypotension by Shapiro et alTopic: sepsisOutcome rating: head turner Several studies (FEAST, CLASSIC) have challenged the benefit of large volumes of fluid for septic shock. The Crystalloid Liberal or Vasopressors Early Resuscitation in Sepsis (CLOVERS) study is an unblinded, randomised multicentre trial conducted at 60 US EDs aiming to establish whether a restrictive fluid strategy outperformed a liberal...
Source: Emergency Medicine Journal - Category: Emergency Medicine Authors: Tags: Journal update Source Type: research