Raftlin and 8-iso-prostaglandin F2 α levels and gene network analysis in patients with Modic changes

ConclusionOur findings indicated that oxidative stress in patients with MC-I may be aggravated and it may cause an inflammation formation of the lesion areas in these patients. Also, the increased 8-iso-PGF2 α and Raftlin levels in patients with MC-II and MC-III may be an adaptive response to against oxidative stress.

http://link.springer.com/10.1007/s00586-023-07757-7

Source: European Spine Journal - May 19, 2023 Category: Orthopaedics Source Type: research