Establishing the safety of selective digestive decontamination within the ICU population: a bridge too far?

ConclusionThe basis for the mortality difference between control and intervention groups of SDD studies remains unclear. Several paradoxical results are consistent with a spillover effect that would conflate the inference of benefit originating from RCCTs. Moreover, this spillover effect would constitute to herd peril.

http://link.springer.com/10.1186/s13063-023-07356-3

Source: Trials - May 17, 2023 Category: Research Source Type: clinical trials