Cancers, Vol. 15, Pages 2747: Preoperative Dose-Escalated Intensity-Modulated Radiotherapy (IMRT) and Intraoperative Radiation Therapy (IORT) in Patients with Retroperitoneal Soft-Tissue Sarcoma: Final Results of a Clinical Phase I/II Trial

Conclusions: The primary endpoint of a 5-year LC of 70% was not met. This might be explained by the inclusion of recurrent disease and the high rate of G3 lesions and leiomyosarcoma, which have been shown to profit less from radiotherapy. Stratification by grading and histology should be considered for future studies.

Source: Cancers - May 13, 2023 Category: Cancer & Oncology Authors: Katharina Seidensaal Matthias Dostal Andreas Kudak Cornelia Jaekel Eva Meixner Jakob Liermann Fabian Weykamp Philipp Hoegen Gunhild Mechtersheimer Franziska Willis Martin Schneider J ürgen Debus Tags: Communication Source Type: research