Expansion at Phila. hospital to create 100+ new jobs

Temple University Health System said Monday it is embarking on a major expansion of the Temple Lung Center, which will create more than 100 new full-time faculty and non-faculty positions at its North Philadelphia campus. The expansion calls for the creation of a new department of thoracic medicine and surgery at Temple that will combine the lung center’s activities into four integrated sections: thoracic surgery; lung transplant; pulmonary, critical care and sleep medicine; and a center for inflammation…
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news

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Conclusion: Our data suggest that mirtazapine can attenuate hepatic innate immune responses that critically regulate the subsequent development of autoimmune liver injury. Therefore, given that it is a safe and widely used medication, mirtazapine may represent a novel therapeutic approach to autoimmune liver disease. Introduction Classically, autoimmune disease was considered a disorder of adaptive immunity (1). However, early innate immune responses are clearly important for driving subsequent adaptive immune responses in autoimmunity. In numerous autoimmune disease models, activation of resident tissue macrophages,...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
In this study, we used HUT as the means to provide an all-encompassing assessment of cardiac and/or peripheral autonomic function in normal controls, SCD subjects and non-SCD subjects with chronic anemia. We hypothesized that by identifying different categories of HUT response among these subjects, we would be able to isolate the autonomic phenotypes that might place SCD subjects at increased risk for microvascular occlusion and VOC. We then employed the causal modeling approach, which utilizes signal analysis and system identification techniques, to probe and disentangle the functional mechanisms involved in the cardiovas...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
Ryan R. Kelly1,2†, Lindsay T. McDonald1,2†, Nathaniel R. Jensen1,2, Sara J. Sidles1,2 and Amanda C. LaRue1,2* 1Research Services, Ralph H. Johnson VA Medical Center, Charleston, SC, United States 2Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC, United States The significant biochemical and physiological effects of psychological stress are beginning to be recognized as exacerbating common diseases, including osteoporosis. This review discusses the current evidence for psychological stress-associated mental health disorders as risk factors for os...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
It’s hardly news that the gastrointestinal tract is important to human health: It transports food from the mouth to the stomach, converts it into absorbable nutrients and stored energy, and shuttles waste back out of the body. If you don’t properly nourish yourself, you don’t live. It’s that simple. But in recent years, scientists have discovered that the GI system has an even bigger, more complex job than previously appreciated. It’s been linked to numerous aspects of health that have seemingly nothing to do with digestion, from immunity to emotional stress to chronic illnesses, including can...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Research Source Type: news
This study provides a possible reason why genes carrying health risks have persisted in human populations. The second found evidence for multiple variants in genes related to ageing that exhibited antagonistic pleiotropic effects. They found higher risk allele frequencies with large effect sizes for late-onset diseases (relative to early-onset diseases) and an excess of variants with antagonistic effects expressed through early and late life diseases. There also exists other recent tangible evidence of antagonistic pleiotropy in specific human genes. The SPATA31 gene has been found under strong positive genomic sele...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Sleep disturbance deteriorates quality of life, and sleep quality of heart failure (HF) patients is worse than that of non-HF patients. In patients with advanced HF, continuous left ventricular assist device (cf-LVAD) is used for the improvement of their quality of life and prognosis. However, the effect on sleep quality of cf-LVAD therapy is unknown. Therefore, this study was aimed to reveal the effect of cf-LVAD on sleep quality.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: 1111 Source Type: research
In conclusion, the presence of SDB is associated with a slight reduction in maximal exercise capacity in LTX recipients, and there is no appreciable relationship between SDB and HRQoL. PMID: 30680642 [PubMed - as supplied by publisher]
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
The diaphragm is the main respiratory muscle. Because possible abnormality of phrenic nerve conduction is reported after cardiothoracic surgery, we aimed to evaluate the function of the diaphragm after LT.Thirty patients (age:42 yrs, LAS:36) were evaluated before, one month(T1) and 3 months(T2) after LT. At each visit, the diaphragm was evaluated in terms of weakness (supine fall of forced vital capacity), electrical activity (CMAPa:compound motor action potential area during phrenic nerve stimulation(PNS)), force (maximal inspiratory pressure and sniff pressure), displacement (abdominal contribution to tidal volume in sup...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Transplantation Source Type: research
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Nowadays, a number of heart failure (HF) patients live with left ventricular assist devices (LVADs) implanted either as a destination therapy or as a bridge to heart transplant or to heart transplant candidacy.1,2 In all these cases, LVAD usually remains for a prolonged time after post-surgical stabilization, during which patients ’ daily quality of life must be improved as much as possible. LVADs are usually set at a fixed number of revolutions per minute (rpm), so that LVAD output changes during daily activities are only preload- and afterload-dependent, with limited variability.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: Original Clinical Science Source Type: research
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