Pagets sykdom i brystvorten

Tidsskr Nor Laegeforen. 2023 Mar 21;143(5). doi: 10.4045/tidsskr.22.0390. Print 2023 Mar 28.ABSTRACTBACKGROUND: Paget's disease of the nipple comprises approximately 1 % of all breast cancers, and presents with unilateral eczematoid changes to the nipple, areola or surrounding skin. Symptoms can be pain, itching or stinging in the area.CASE PRESENTATION: A female patient in her sixties presented to the skin clinic 18 months after initial detection of a rash surrounding her left nipple. Earlier ultrasound and mammography had not indicated pathology. Clinical suspicion and punch biopsies revealed a ductal carcinoma in situ. Surgical excision had to be repeated three times before the underlying malignancy was totally removed.INTERPRETATION: Eczematoid changes in the nipple area are associated with underlying ductal carcinoma or a carcinoma in situ, and biopsies should be taken.PMID:36987906 | DOI:10.4045/tidsskr.22.0390
Source: Tidsskrift for den Norske Laegeforening - Category: General Medicine Authors: Source Type: research