A new butylphthalide from < em > Ligusticum striatum < /em > DC

Nat Prod Res. 2023 Apr 12:1-8. doi: 10.1080/14786419.2023.2200944. Online ahead of print.ABSTRACTOne new butylphthalide ligusticumolide H (1), together with the known butylphthalides senkyunolide I (2), senkyunolide H (3), (3 R,3'S)-3'-hydroxy-3-butylphthalide (4), (3 R)-4-hydroxy-3-butylphthalide (5) and senkyunolide C (6) was isolated from the rhizome of Ligusticum striatum DC. Their structures were determined by extensive spectroscopic analyses including HR-ESI-MS, 1D and 2D NMR, and the absolute configuration of 1 was established by NMR and ECD calculations. Their effect on NO production in IL-1β-stimulated chondrocytes was also evaluated.PMID:37042678 | DOI:10.1080/14786419.2023.2200944
Source: Natural Product Research - Category: Biochemistry Authors: Source Type: research
More News: Biochemistry