Study suggests need for renal protective care in pediatric lung transplant patients

Caucasian and Hispanic children who undergo lung transplantation appear to be at greater risk for developing chronic kidney disease, or CKD, than other children, according to a small retrospective study.
Source: ScienceDaily Headlines - Category: Science Source Type: news

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We learn from basic physiology  lessons that human body is made up of 60 % water. What about heart ? There is no reason for the heart should behave differently from rest of the body . If my  assumptions are correct when the normal heart weighs 300g  , 180g of which should be  be water. The same thing could be applicable for LV mass( * Reference requested) Is there myocardial congestion in cardiac failure ? Genesis of edema in any tissue depends on local hydrostatic pressures, tissue resistive forces, osmotic balance, and cell membrane permeability. In the myocardium individual contri...
Source: Dr.S.Venkatesan MD - Category: Cardiology Authors: Tags: cardiac failure Cardiac MRI Cardio Nephrology effect of dialysis on myocardial water content lv amss and myocardial edema myocardial edema and ckd chronic kidney failure myocardial interstitial edema myocardial water imaging water logging Source Type: blogs
IntroductionBased on improvement of overall survival (OS), lenalidomide (R) maintenance after up-front autologous stem cell transplantation has recently been approved for multiple myeloma (MM) patients (pts). Conversely, in transplant non-eligible (TNE) pts R maintenance after R-based induction improved progression free survival (PFS) but had no impact on OS. First-line treatment with VMP is considered a standard of care for newly diagnosed (ND) TNE pts, but whether maintenance therapy with R after VMP induction can further improve PFS and OS is currently unknown.AimsThe prospective phase IIb GERMAIN trial (EudraCT-No: 201...
Source: Blood - Category: Hematology Authors: Tags: 653. Myeloma: Therapy, excluding Transplantation: Poster I Source Type: research
Infection with the hepatitis C virus (HCV) has adverse liver, kidney, and cardiovascular consequences in patients with chronic kidney disease (CKD), including those on dialysis therapy and in those with a kidney transplant. Since the publication of the original Kidney Disease: Improving Global Outcomes (KDIGO) HCV Guideline in 2008, major advances in HCV management, particularly with the advent of direct-acting antiviral therapies, have now made the cure of HCV possible in CKD patients. In addition, diagnostic techniques have evolved to enable the noninvasive diagnosis of liver fibrosis.
Source: Kidney International - Category: Urology & Nephrology Authors: Tags: Guideline Summary Source Type: research
Conditions:   Lung Transplant; Complications;   Chronic Kidney Diseases Intervention:   Sponsor:   University of Giessen Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Lung Transplant; Complications;   Chronic Kidney Diseases Intervention:   Sponsor:   University of Giessen Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Lung Transplant; Complications;   Chronic Kidney Diseases Intervention:   Sponsor:   University of Giessen Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Lung Transplant; Complications;   Chronic Kidney Diseases Intervention:   Sponsor:   University of Giessen Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Lung Transplant; Complications;   Chronic Kidney Diseases Intervention:   Sponsor:   University of Giessen Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Improved renal function following ventricular assist device (VAD) placement is seen in some, but not all VAD recipients. Failure to improve may indicate enduring renal injury. We hypothesized that VAD implantation results in improved renal function in the majority of pediatric patients with heart failure and that failure to improve would predict poor renal outcomes after heart transplantation (HT).
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research
There is limited data to guide dual organ allocation in pts implanted with left ventricular assist device with bridge to transplant intention with chronic kidney disease (CKD). The goal of our study was to determine survival outcomes post transplant in LVAD patients with CKD who either received heart transplant alone (HTA) or heart kidney transplant( HKTx).
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research
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