Induction of Canonical Wnt Signaling by Synovial Overexpression of Selected Wnts Leads to Protease Activity and Early Osteoarthritis-Like Cartilage Damage.
In conclusion, our data show that canonical Wnts and WISP1, which we found overexpressed in the synovium during experimental OA, may conduce to OA pathology.
PMID: 25976248 [PubMed - as supplied by publisher]
Source: The American Journal of Pathology - Category: Pathology Authors: van den Bosch MH, Blom AB, Sloetjes AW, Koenders MI, van de Loo FA, van den Berg WB, van Lent PL, van der Kraan PM Tags: Am J Pathol Source Type: research
More News: Osteoarthritis | Pathology